Alterations in serum thiol-disulfiide homeostasis and ischemiamodifiied albumin concentrations in clinical canine parvoviral enteritis

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dc.authoridNeşelioğlu, Salim/0000-0002-0974-5717
dc.contributor.authorŞenel, Yasin
dc.contributor.authorTerzi, Osman Safa
dc.contributor.authorKara, Erdal
dc.contributor.authorErel, Özcan
dc.contributor.authorNeşelioğlu, Salim
dc.contributor.authorCeylan, Ebubekir
dc.date.accessioned2025-01-21T16:33:54Z
dc.date.available2025-01-21T16:33:54Z
dc.date.issued2024
dc.departmentKırıkkale Üniversitesi
dc.description.abstractMonitoring biomarkers related to inflammation and oxidative stress is critical in dogs because parvovirus causes both inflammatory and antioxidant alterations. The aim of this study was to investigate inflammatory and antioxidant changes caused by canine parvoviral enteritis to better understand the oxidative stress process related to this disease. Thus, the total thiol, native thiol, disulfide, and ischemia-modified albumin levels of Canine parvovirus infected symptomatic puppies and healthy puppies were examined. Using the results of complete blood counts, the blood serum thiol-disulfide homeostasis and ischemia modified albumin levels of the puppies with Canine parvoviral enteritis (n = 65) and the healthy puppies (n = 34) were compared. Canine parvoviral enteritis and control groups showed a statistically significant difference in thiol disulfide levels (p < 0.01), while no significant difference was observed in ischemia modified albumin levels between the two groups. As a result of this study, a picture contradictory to the literature information was discovered; it is believed that integrating research on oxidative stress at various stages of disease progression, including the early stage, clinical period and recovery processes may provide more information about the dynamics of oxidative stress during disease progression.
dc.identifier.doi10.55730/1300-0128.4341
dc.identifier.issn1300-0128
dc.identifier.issue2
dc.identifier.scopus2-s2.0-85190131914
dc.identifier.scopusqualityQ3
dc.identifier.trdizinid1242542
dc.identifier.urihttps://doi.org/10.55730/1300-0128.4341
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay1242542
dc.identifier.urihttps://hdl.handle.net/20.500.12587/23879
dc.identifier.volume48
dc.identifier.wosWOS:001200791600002
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherTubitak Scientific & Technological Research Council Turkey
dc.relation.ispartofTurkish Journal of Veterinary & Animal Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241229
dc.subjectCanine parvoviral enteritis; ischemia modified albumin; oxidative stress; thiol-disulfide homeostasis
dc.titleAlterations in serum thiol-disulfiide homeostasis and ischemiamodifiied albumin concentrations in clinical canine parvoviral enteritis
dc.typeArticle

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