Dual benefit from intramuscular interferon-beta treatment in a patient with multiple sclerosis and chronic hepatitis-C virus infection

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dc.contributor.authorTan, F.U.
dc.contributor.authorCetinkaya, H.
dc.contributor.authorErden, E.
dc.contributor.authorUlkatan, S.
dc.contributor.authorAydin, N.
dc.date.accessioned2020-06-25T17:34:57Z
dc.date.available2020-06-25T17:34:57Z
dc.date.issued2002
dc.departmentKırıkkale Üniversitesi
dc.descriptionULKATAN, SEDAT/0000-0002-9288-7635
dc.description.abstractIn patients with hepatitis C virus infection interferon-beta therapy is most effective when administered by the intravenous route. However we would like to present a patient with multiple sclerosis and chronic hepatitis C virus infection who obtained dual benefit from intramuscular interferon-beta therapy. Intramuscular interferon-beta1a (Avonex) 6 million U/week was started for prevention of attacks in a 32-year-old woman with multiple sclerosis. She had acquired hepatitis C virus infection from blood transfusion during a Caesarean section. Although serum transaminases were within normal limits anti-hepatitis C virus test by ELISA and hepatitis C virus RNA by polymerase chain reaction were positive. Liver biopsy revealed chronic persistent hepatitis. Considering the use of interferon-beta1a for multiple sclerosis prophylaxis and the stage of hepatitis the patient was not offered any additional treatment. Repeat liver biopsy performed after one year showed the absence of previous findings. The patient has also cleared the hepatitis-C virus RNA.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.endpage1687en_US
dc.identifier.issn0172-6390
dc.identifier.issue48en_US
dc.identifier.pmid12397766
dc.identifier.scopus2-s2.0-0036839910
dc.identifier.scopusqualityN/A
dc.identifier.startpage1686en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12587/2965
dc.identifier.volume49en_US
dc.identifier.wosWOS:000178568600057
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherH G E Update Medical Publishing S Aen_US
dc.relation.ispartofHepato-Gastroenterology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjecthepatitis Cen_US
dc.subjecttreatmenten_US
dc.subjectinterferon-betaen_US
dc.titleDual benefit from intramuscular interferon-beta treatment in a patient with multiple sclerosis and chronic hepatitis-C virus infectionen_US
dc.typeArticle

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