PLATELET TO LYMPHOCYTE RATIO AS A PREDICTIVE BIOMARKER FOR PREOPERATIVE DIAGNOSIS OF PARATHYROID ADENOMA

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dc.contributor.authorAydın, Oktay
dc.contributor.authorPehlivanlı, Faruk
dc.date.accessioned2025-01-21T16:16:46Z
dc.date.available2025-01-21T16:16:46Z
dc.date.issued2019
dc.departmentKırıkkale Üniversitesi
dc.description.abstractObjective: There is a significant increase in studies concerningthe use of platelet to lymphocyte ratio (PLR) and neutrophil tolymphocyte ratio (NLR) for diagnosis and prognosis in manyinflammatory and malignant diseases. The idea that PLR andNLR can be used as a biomarker attracts many researchers tothis area. The aim of this retrospective case control study was toinvestigate the role of PLR and NLR values in diagnosis of theparathyroid adenoma.Material and Methods: In this study, 17 patients withparathyroid adenoma (PAD group) were included and the PLRand NLR values of these patients were compared with controlgroup (15 participants) consisted of healthy subjects.Results: The lymphocyte count values of the PAD group weresignificantly higher than those of the CONTROL group. Theplatelet count and NLR values were not different between thegroups. The PLR values of the PAD group were significantlylower than those of the CONTROL groups. ROC-Curve analysisresults showed that if platelet to lymphocyte ratio value was<125, it could be a specific and sensitive biomarker indiscrimination of patients with parathyroid adenoma fromhealthy individuals.Conclusion: In conclusion, low PLR values measured inpatients with primary hyperparathyroidism could be a newpreoperative diagnostic biomarker for parathyroid adenoma.
dc.identifier.doi10.24938/kutfd.522955
dc.identifier.endpage79
dc.identifier.issn2148-9645
dc.identifier.issue1
dc.identifier.startpage73
dc.identifier.trdizinid414861
dc.identifier.urihttps://doi.org/10.24938/kutfd.522955
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/414861
dc.identifier.urihttps://hdl.handle.net/20.500.12587/22495
dc.identifier.volume21
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofKırıkkale Üniversitesi Tıp Fakültesi Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241229
dc.subjectEndokrinoloji ve Metabolizma
dc.subjectGenel ve Dahili Tıp
dc.titlePLATELET TO LYMPHOCYTE RATIO AS A PREDICTIVE BIOMARKER FOR PREOPERATIVE DIAGNOSIS OF PARATHYROID ADENOMA
dc.typeArticle

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