The Adjunctive Effect of Platelet-Rich Fibrin to Connective Tissue Graft in the Treatment of Buccal Recession Defects: Results of a Randomized, Parallel-Group Controlled Trial

dc.contributor.authorKeçeli, Hüseyin Gencay
dc.contributor.authorKamak, Gülen
dc.contributor.authorErdemir, Ebru Olgun
dc.contributor.authorEvginer, Mustafa Serdar
dc.contributor.authorDolgun, Anıl
dc.date.accessioned2020-06-25T18:12:42Z
dc.date.available2020-06-25T18:12:42Z
dc.date.issued2015
dc.departmentKırıkkale Üniversitesi
dc.descriptionDolgun, Anil Barak/0000-0002-2693-0666; Bayram, Cem/0000-0001-8717-4668
dc.description.abstractBackground: Platelet-rich fibrin (PRF) is an autologous preparation that has encouraging effects in healing and regeneration. The aim of this trial is to evaluate the effectiveness of coronally advanced flap (CAF) + connective tissue graft (CTG) + PRF in Miller Class I and II recession treatment compared to CAF + CTG. Methods: Forty patients were treated surgically with either CAF + CTG + PRF (test group) or CAF + CTG (control group). Clinical parameters of plaque index, gingival index, vertical recession (VR), probing depth, clinical attachment level (CAL), keratinized tissue width (KTW), horizontal recession (HR), mucogingival junction localization, and tissue thickness (TT) were recorded at baseline and 3 and 6 months after surgery. Root coverage (RC), complete RC (CRC), attachment gain (AG), and keratinized tissue change (KTC) were also calculated. Results: All individuals completed the entire study period. At baseline, mean VR, HR, CAL, KTW, and TT values were similar (P > 0.05). In both groups, all parameters showed significant improvement after treatment (P < 0.001), and except TT (P < 0.05), no intergroup difference was observed at 6 months after surgery. The amount of RC and AG, but not KTC and CRC, was higher in the PRF-applied group (P < 0.05). Conclusions: According to the results, the addition of PRF did not further develop the outcomes of CAF + CTG treatment except increasing the TT. However, this single trial is not sufficient to advocate the true clinical effect of PRF on recession treatment with CAF + CTG, and additional trials are needed.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1902/jop.2015.150015
dc.identifier.endpage1230en_US
dc.identifier.issn0022-3492
dc.identifier.issn1943-3670
dc.identifier.issue11en_US
dc.identifier.pmid26177630
dc.identifier.scopus2-s2.0-84946048538
dc.identifier.scopusqualityQ1
dc.identifier.startpage1221en_US
dc.identifier.urihttps://doi.org/10.1902/jop.2015.150015
dc.identifier.urihttps://hdl.handle.net/20.500.12587/6014
dc.identifier.volume86en_US
dc.identifier.wosWOS:000364162600005
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWileyen_US
dc.relation.ispartofJournal Of Periodontology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectConnective tissueen_US
dc.subjectgingivaen_US
dc.subjectgingival recessionen_US
dc.subjectplatelet-rich plasmaen_US
dc.subjecttissue transplantationen_US
dc.subjectsurgical flapsen_US
dc.titleThe Adjunctive Effect of Platelet-Rich Fibrin to Connective Tissue Graft in the Treatment of Buccal Recession Defects: Results of a Randomized, Parallel-Group Controlled Trialen_US
dc.typeArticle

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