The evaluation of cognitive functions in desflurane anesthesia with low and high flow

Basit Öğe Kaydı
dc.contributor.authorKaymak, Çetin
dc.contributor.authorKoçak, Orhan Murat
dc.contributor.authorBabadağ, Yücel
dc.contributor.authorKoçak, Emine
dc.contributor.authorApan, Alparslan
dc.date.accessioned2020-06-25T15:14:40Z
dc.date.available2020-06-25T15:14:40Z
dc.date.issued2011
dc.departmentKırıkkale Üniversitesi
dc.description.abstractObjective: Cognitive function consists of the level of consciousness, memory, orientation, concentration, general knowledge, intelligence, understanding and judgment. Postoperative cognitive dysfunction is a multifactor state which is characterized by disability of memory and concentration. At the recovery stage, the patient's cognitive functions returning to its original level is closely related with pharmacokinetics of the anesthetic material, anesthesia, desfluran used in low and high flow anesthesia. This study aimed at examining cognitive functions in the preoperative ve postoperative period when low and high flow of desfluran anesthesia was applied. Methods: After Institutional Ethics Committee approval, ASA I/II, 32 patients of 15-55 ages two groups. One group (Group I, n=16) had high flow and the other (Group II, n=I6) had low flow. Premedication was not applied. Anesthesia was induced with 1.5 ?g kg-1 fentanyl and 5-7 mg kg-1 thiopental. Endotracheal intubation was performed after 0.6 mg kg-1 rocuronium. Patients, included in Group I and in Group II were applied 4 L min-1 50 % N 2O+O2 and 1 L min-1 50 % N2O+O 2 respectively. Patient's recovery parameters were evaluated with Modified Aldrete Score (MAS) at 5., 10., 15., 30. and 60. minutes. Cognitive functions of the patients were evaluated with Verbal Auditory Memory Test (VAMT) and Stroop Interference Test (SIT). Results: No significant result was found in the preoperative and postoperative VAMT 1, VAMT 5, VAMT 6, VAMT 7, VAMT 8 and SIT scores between Group I and Group II. No correlation was confirmed between postoperative recovery time and VAMT 1, VAMT 5, VAMT 6, VAMT 7, VAMT 8, SIT score. Conclusion: Neither of the anesthetic techniques showed differences with respect to cognitive functions. We conclude that since no relationship between postoperative recovery time and cognitive functions was found, the amount of fresh gas used in the desfluran did not affect the cognitive functions.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.endpage129en_US
dc.identifier.issn13000578
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-79960752136
dc.identifier.scopusqualityQ4
dc.identifier.startpage124en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12587/2169
dc.identifier.volume19en_US
dc.indekslendigikaynakScopus
dc.language.isotr
dc.relation.ispartofAnestezi Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCognitive dysfunctionen_US
dc.subjectControlled hypotensionen_US
dc.subjectDesfluraneen_US
dc.subjectLow-Flow anesthesiaen_US
dc.titleThe evaluation of cognitive functions in desflurane anesthesia with low and high flowen_US
dc.title.alternativeYÜKSEK VE DÜŞÜK AKIMLI DESFLURAN ANESTEZİSİNDE KOGNİTİF FONKSİYONLARIN DEĞERLENDİRİLMESİen_US
dc.typeArticle

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