IL-6 and IL-8 levels in GCF of the teeth supporting fixed partial denture

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dc.contributor.authorErdemir, E. O.
dc.contributor.authorBaran, I.
dc.contributor.authorNalcaci, R.
dc.contributor.authorApan, T.
dc.date.accessioned2020-06-25T17:51:29Z
dc.date.available2020-06-25T17:51:29Z
dc.date.issued2010
dc.departmentKırıkkale Üniversitesi
dc.description.abstractObjectives: To evaluate the gingival crevicular fluid (GCF) contents of interleukin-6 (IL-6) and interleukin-8 (IL-8) and the clinical parameters of the teeth supporting fixed partial denture (FPD) and the contralateral teeth and to assess the effect of scaling and root planning (SRP) on clinical parameters and the GCF levels of cytokines. Materials and methods: The study population included 23 patients. Probing depth (PD), clinical attachment level (CAL), plaque index (PI), and gingival index (GI) were recorded, and GCF samples were collected for analysis of cytokine levels from the teeth with FPD (Test Group), the contralateral teeth (Control Group) of each participant at baseline. After initial measurements, all participants received primary phase of non-surgical treatment including oral hygiene instruction and scaling and root planning (SRP). At the 1st month and the 3rd month after SRP, these procedures were repeated. Results: In both groups, all clinical parameters and the total amount of IL-8 showed decreases from initial to the 3rd month (P < 0.05), but from the 1st month to the 3rd month; PD, PI, and GI values significantly increased in the test group (P < 0.05). Conclusion: The non-surgical periodontal treatment reduced the total amount of IL-8, not IL-6, and the clinical parameters of the teeth with FPD and contralateral teeth. But, there was a trend to the higher levels of PD, PI, and GI in the teeth with FPD. Therefore, a regular program for dental prophylaxis is also important for the maintenance of periodontal health in patients with FPD.en_US
dc.description.sponsorshipResearch Fund of Kirikkale University, TurkeyKirikkale Universityen_US
dc.description.sponsorshipThis study was supported in part by a grant from the Research Fund of Kirikkale University, Turkey. The expert statistical advice of Osman Caglayan is gratefully acknowledged.en_US
dc.identifier.citationErdemir, E., Baran, I., Nalcaci, R. and Apan, T. (2010), IL-6 and IL-8 levels in GCF of the teeth supporting fixed partial denture. Oral Diseases, 16: 83-88.en_US
dc.identifier.doi10.1111/j.1601-0825.2009.01621.x
dc.identifier.endpage88en_US
dc.identifier.issn1354-523X
dc.identifier.issue1en_US
dc.identifier.pmid19735454
dc.identifier.scopus2-s2.0-73649146524
dc.identifier.scopusqualityQ1
dc.identifier.startpage83en_US
dc.identifier.urihttps://doi.org/10.1111/j.1601-0825.2009.01621.x
dc.identifier.urihttps://hdl.handle.net/20.500.12587/4877
dc.identifier.volume16en_US
dc.identifier.wosWOS:000272866700013
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWiley-Blackwell Publishing, Incen_US
dc.relation.ispartofOral Diseases
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectIL-6en_US
dc.subjectIL-8en_US
dc.subjectGingival crevicular fluiden_US
dc.subjectfixed partial dentureen_US
dc.subjectnon-surgical therapyen_US
dc.titleIL-6 and IL-8 levels in GCF of the teeth supporting fixed partial dentureen_US
dc.typeArticle

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