Chronic airway diseases in adult life and childhood infections

dc.contributor.authorEkici, Mehmet
dc.contributor.authorEkici, Aydanur
dc.contributor.authorAkin, Ahmet
dc.contributor.authorAltinkaya, Volkan
dc.contributor.authorBulcun, Emel
dc.date.accessioned2020-06-25T17:48:05Z
dc.date.available2020-06-25T17:48:05Z
dc.date.issued2008
dc.description.abstractBackground: Respiratory disorders in childhood may predispose to pulmonary disease in late adult life. Objectives: The aim of this study was to evaluate the relationship between their effects in adult life and the characteristics of the respiratory system in childhood. Methods: A total of 10,224 parents and grandparents of students from 14 randomly selected primary schools in the city center were asked to answer questionnaires given to their children. 9,853 of 10,224 persons (the overall response rate was 96.3%) were eligible for analysis. In the questionnaire subjects were asked about respiratory system-related symptoms and characteristics. Results: Chronic cough [14.3 vs. 4.7%, OR 3.4 (2.6 - 4.4), p < 0.001], chronic bronchitis [35.3 vs. 11.8%, OR 4.0 (3.4 - 4.8), p ! 0.001] and asthma [34.2 vs. 5.1%, OR 9.6 (8.0 - 11.5), p < 0.001] in the childhood respiratory infection group were more common than in the control group. Childhood respiratory infections were associated with an increased risk of asthma (OR 5.6, p < 0.001), chronic bronchitis (OR 2.3, p < 0.001) and chronic cough (OR 1.5, p < 0.001), after adjusting for possible confounding factors. In addition, the presence of dampness or visible mould, wall-to-wall carpets, pets at home and parents' smoking during childhood were associated with an increased risk of frequent childhood respiratory infections. Conclusion: These results indicated that frequent respiratory infections during childhood might play an important role in the occurrence of chronic airway diseases in adult life. The removing of risk factors for frequent childhood respiratory infections may reduce the subsequent risk of chronic airway disease in late adult life. Copyright (C) 2007 S. Karger AG, Basel.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1159/000102952
dc.identifier.endpage59en_US
dc.identifier.issn0025-7931
dc.identifier.issn1423-0356
dc.identifier.issue1en_US
dc.identifier.pmid17505127
dc.identifier.scopus2-s2.0-38049026840
dc.identifier.scopusqualityQ1
dc.identifier.startpage55en_US
dc.identifier.urihttps://doi.org10.1159/000102952
dc.identifier.urihttps://hdl.handle.net/20.500.12587/4296
dc.identifier.volume75en_US
dc.identifier.wosWOS:000252386000011
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherKargeren_US
dc.relation.ispartofRespiration
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectchildhood respiratory infectionen_US
dc.subjectparents' smokingen_US
dc.subjectasthmaen_US
dc.subjectbronchitis, chronicen_US
dc.subjectcough, chronicen_US
dc.titleChronic airway diseases in adult life and childhood infectionsen_US
dc.typeArticle

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