The resistance of Gram-negative rods against isepamicin and other aminoglycosides
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Tarih
2005
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Aves
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
This study was conducted to investigate the resistance of Gram-negative rods against isepamicin and other aminoglycosides. Resistance against five different aminoglycosides were tested in 861 Gram-negative microorganisms which were isolated in nosocomial infections, including 546 Escherichia coli, 116 Proteus spp., 87 Klebsiella spp., 56 Enterobacter spp. and 56 nonfermentative bacteria. The microorganisms from various infection sites tested by using the disk diffusion method according to NCCLS recommendations. The resistance rates of all Gram-negative bacteria included in the study were 0.8% for isepamicin, 2.0% for amikacin, 2.1% for netilmicin, 5.9% for gentamicin and 7.9% for tobramycin. We conclude that isepamicin is the aminoglycoside with highest activity, and tobramycin with highest resistance rate. The resistance of aminoglycoside should be controlled and the use of rational antibiotic should be taken into condideration in nosocomial infections.
Açıklama
Anahtar Kelimeler
Aminoglycoside; isepamicin; Gram; negative bacteria
Kaynak
Klimik Journal
WoS Q Değeri
N/A
Scopus Q Değeri
Cilt
18
Sayı
1
