The resistance of Gram-negative rods against isepamicin and other aminoglycosides

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dc.contributor.authorKaygusuz, Sedat
dc.contributor.authorAyaşlıoğlu, Ergin
dc.contributor.authorÖzlük, Özlem
dc.contributor.authorKılıç, Dilek
dc.date.accessioned2025-01-21T16:55:16Z
dc.date.available2025-01-21T16:55:16Z
dc.date.issued2005
dc.departmentKırıkkale Üniversitesi
dc.description.abstractThis study was conducted to investigate the resistance of Gram-negative rods against isepamicin and other aminoglycosides. Resistance against five different aminoglycosides were tested in 861 Gram-negative microorganisms which were isolated in nosocomial infections, including 546 Escherichia coli, 116 Proteus spp., 87 Klebsiella spp., 56 Enterobacter spp. and 56 nonfermentative bacteria. The microorganisms from various infection sites tested by using the disk diffusion method according to NCCLS recommendations. The resistance rates of all Gram-negative bacteria included in the study were 0.8% for isepamicin, 2.0% for amikacin, 2.1% for netilmicin, 5.9% for gentamicin and 7.9% for tobramycin. We conclude that isepamicin is the aminoglycoside with highest activity, and tobramycin with highest resistance rate. The resistance of aminoglycoside should be controlled and the use of rational antibiotic should be taken into condideration in nosocomial infections.
dc.identifier.endpage40
dc.identifier.issn1301-143X
dc.identifier.issn1309-1484
dc.identifier.issue1
dc.identifier.startpage38
dc.identifier.urihttps://hdl.handle.net/20.500.12587/25747
dc.identifier.volume18
dc.identifier.wosWOS:000420789400010
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.language.isotr
dc.publisherAves
dc.relation.ispartofKlimik Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241229
dc.subjectAminoglycoside; isepamicin; Gram; negative bacteria
dc.titleThe resistance of Gram-negative rods against isepamicin and other aminoglycosides
dc.typeArticle

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