Use of methylphenidate for attention-deficit hyperactivity disorder in patients with epilepsy or electroencephalographic abnormalities

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dc.contributor.authorGucuyener, K.
dc.contributor.authorErdemoglu, A.K.
dc.contributor.authorSenol, S.
dc.contributor.authorSerdaroglu, A.
dc.contributor.authorSoysal, S.
dc.contributor.authorKockar, A.I.
dc.date.accessioned2020-06-25T17:35:36Z
dc.date.available2020-06-25T17:35:36Z
dc.date.issued2003
dc.departmentKırıkkale Üniversitesi
dc.description.abstractMethylphenidate is commonly believed to lower seizure threshold. The safe use of methylphenidate has not been clarified in patients with attention-deficit hyperactivity disorder (ADHD) and concomitant active seizure or electroencephalographic (EEG) abnormalities. Patients with ADHD and active seizures (n = 57) and patients with ADHD and EEG abnormalities (n = 62), 6 to 16 years of age, were included in the study. The safety and efficacy of treatment with antiepilepsy drugs combined with methylphenidate were determined by assessing seizure frequency, changes in ADHD symptoms, the Conners' Rating Scales, EEG differences, and side effects. The Conners' Rating Scales, performed by parents and teachers, and mean total ADHD symptom scores at the beginning of the study and at the end were significantly different (P = .05 for the Conners' Rating Scales and P = .001 for ADHD symptom scores). Methylphenidate had a beneficial effect on EEG. Seizure frequency did not change from baseline. The side effects of methylphenidate were mild and transient. Methylphenidate is safe and effective in children with ADHD and concomitant active seizures or EEG abnormalities.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1177/08830738030180020601
dc.identifier.endpage112en_US
dc.identifier.issn0883-0738
dc.identifier.issn1708-8283
dc.identifier.issue2en_US
dc.identifier.pmid12693777
dc.identifier.scopus2-s2.0-0345700831
dc.identifier.scopusqualityQ1
dc.identifier.startpage109en_US
dc.identifier.urihttps://doi.org/10.1177/08830738030180020601
dc.identifier.urihttps://hdl.handle.net/20.500.12587/3163
dc.identifier.volume18en_US
dc.identifier.wosWOS:000181922500005
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSage Publications Incen_US
dc.relation.ispartofJournal Of Child Neurology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleUse of methylphenidate for attention-deficit hyperactivity disorder in patients with epilepsy or electroencephalographic abnormalitiesen_US
dc.typeArticle

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