Therapeutic Plasma Exchange in Pediatric Patients: Results from a Single Center

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dc.contributor.authorDalkiran, Tahir
dc.contributor.authorMercan, Mehmet
dc.contributor.authorIpek, Sevcan
dc.contributor.authorGullu, Ufuk Utku
dc.contributor.authorKandur, Yasar
dc.contributor.authorAcipayam, Can
dc.contributor.authorDilber, Cengiz
dc.date.accessioned2025-01-21T16:55:25Z
dc.date.available2025-01-21T16:55:25Z
dc.date.issued2024
dc.departmentKırıkkale Üniversitesi
dc.description.abstractTherapeutic plasma exchange (TPE) can be applied as an effective therapeutic option in children with hematological, neurological, nephrological, and autoimmune/rheumatic disorders. We aimed to report our TPE experience in pediatric patients. In this article, we retrospectively reviewed the records of pediatric patients who underwent TPE between 2019 and 2021. A total of 128 TPE sessions were performed in 25 patients (13 males,12 females; mean age 59.6 +/- 11.7 [3-198] months). The TPE indications were sepsis with/without multiorgan dysfunction syndrome in five patients, acute liver failure, hemolytic uremic syndrome caused by Shiga toxin, and autoimmune hemolytic anemia in three patients, respectively, multiple sclerosis, autoimmune encephalitis, and multisystem inflammatory syndrome in children (MIS-C) in two patients each, and myasthenia gravis crisis, meningococcemia, hemolytic uremic syndrome caused by coronavirus disease 2019, hemophagocytic lymphohistiocytosis, autoimmune encephalitis, and metabolic disease (fatty acid oxidation defect, liver failure) in one patient each. Based on our findings, we proposed that the American Society for Apheresis criteria should be updated according to newly described clinical conditions such as MIS-C.
dc.identifier.doi10.1055/s-0041-1742252
dc.identifier.endpage285
dc.identifier.issn2146-4618
dc.identifier.issn2146-4626
dc.identifier.issue3
dc.identifier.pmid39629152
dc.identifier.startpage282
dc.identifier.urihttps://doi.org/10.1055/s-0041-1742252
dc.identifier.urihttps://hdl.handle.net/20.500.12587/25779
dc.identifier.volume13
dc.identifier.wosWOS:000750544400002
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherGeorg Thieme Verlag Kg
dc.relation.ispartofJournal of Pediatric Intensive Care
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241229
dc.subjecttherapeutic plasma exchange; American Society for Apheresis guidelines; multisystem inflammatory syndrome in children
dc.titleTherapeutic Plasma Exchange in Pediatric Patients: Results from a Single Center
dc.typeArticle

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