Differences in autonomic activity in individuals with optimal, normal, and high-normal blood pressure levels
Yükleniyor...
Tarih
2010
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Objectives: We investigated differences in autonomic activity in normotensive individuals having optimal, normal and high-normal blood pressure (BP) levels according to the guidelines of the European Society of Hypertension and European Society of Cardiology (ESH/ESC). Study design: The study included 294 normotensive subjects (135 males, 159 females; age range 16 to 75 years) with similar clinical, morphometric, biochemical, electrocardiographic, and echocardiographic features. The subjects were classified into the following BP groups: group 1 (n=113) with optimal BP (<120/80 mmHg); group 2 (n=104) with normal BP (120-129/80-84 mmHg), and group 3 (n=77) with high-normal BP (130-139/85-89 mmHg). All the subjects underwent 24-hour Holter monitoring to obtain heart rate variability (HRV) parameters of 24-hour, daytime, and nighttime periods. Normalized low (LF n) and high (HF n) frequency powers, and logarithmic (Log) values of HRV parameters were also calculated. Results: On 24-hour Holter monitoring, heart rates were similar in three groups. Compared to group 1 and 2, group 3 exhibited significantly higher LF/HF (p<0.001) and LF n (p=0.001) values, and significantly lower HF n (p=0.001), pNN50 (p=0.001), and rMSSD (p=0.005) values. There were no significant differences between the groups with respect to daytime HRV parameters; however, nighttime LF/HF, LF n, and HF n values were significantly different between the groups. Log LF/HF values obtained during the 24-hour and nighttime periods showed significant differences between group 1 and group 3 (for 24 hours, p<0.001; for night, p=0.001) and between group 2 and group 3 (for 24 hours, p<0.001; for night, p=0.009), but group 1 and group 2 did not differ significantly in this respect (p>0.05). Conclusion: These findings suggest that subjects with high-normal BP have increased sympathetic activity and decreased parasympathetic activity, possibly making them more liable to hypertension.
Açıklama
Anahtar Kelimeler
Ambulatory, Autonomic nervous system, Blood pressure, Electrocardiography, Heart rate, Hypertension
Kaynak
Turk Kardiyoloji Dernegi Arsivi
WoS Q Değeri
Scopus Q Değeri
Q3
Cilt
38
Sayı
3
Künye
Doğru, M. T., Şimşek, V., Şahin, Ö., Özer, N. (2010). Differences in autonomic activity in individuals with optimal, normal, and high-normal blood pressure levels. Türk Kardiyoloji Derneği Arşivi, 38(3), 182 - 188.
