The effect of albendazole and praziquantel on Strobilocercus fasciolaris in experimentally infected mice

Simple item page
dc.contributor.authorYildiz, K.
dc.contributor.authorDoganay, A.
dc.date.accessioned2020-06-25T17:34:54Z
dc.date.available2020-06-25T17:34:54Z
dc.date.issued2001
dc.departmentKırıkkale Üniversitesi
dc.descriptionYILDIZ, Kader/0000-0001-5802-6156
dc.description.abstractThis study was conducted to analyze the effects of albendazole and praziquantel on the development and treatment of S. fasciolaris. In order to determine the prophylactic effects on the development of S. fasciolaris, the drugs (albendazole and praziquantel) were given 2 days before the infection and for a period of 30 days. Also, to determine the effects of treatment, both drugs were given on the 63(rd) day of the infection and for a period of 14 days. The dosages of albendazole and praziquantel were 15 mg/kg (150 ppm) and 200 mg/kg (2000 ppm) respectively. They were given with the normal daily diet. In the group in which albendazole had a prophylactive effect on the development of S. fasciolaris, no macroscopic cystic development was observed. However, in the histological sections of the livers, some microscopic cystic structures were found. In the group in which the effects of the drug were tested ail the cysts were affected. In the group in which the prophylactic effects of praziquantel on cyst development were tested, it was observed that the drug had no effect on the development of cysts, but compared to the positive control group (no drugs given), the drug reduced the number of cysts in the liver. The effects of praziquantel on the developing S. fasciolaris were calculated to be 27.2%, The preventive effect of praziquantel on the developed S. fasciolaris was calculated to be 93.4%. As a result, while prophylactic effects of albendazole on the development of S. fasciolaris were observed, no such effects were observed with praziquantel. Both drugs were effective in the treatment of developing cysts.en_US
dc.identifier.citationYıldız, K. and Doğanay, A. (2001) "The Efffect of Albendazole and Praziquantel on Strobilocercus fasciolaris in Experimentally Infected Mice," Turkish Journal of Veterinary & Animal Sciences: 25(3), Article 12. Available at: https://journals.tubitak.gov.tr/veterinary/vol25/iss3/12en_US
dc.identifier.endpage294en_US
dc.identifier.issn1300-0128
dc.identifier.issue3en_US
dc.identifier.startpage287en_US
dc.identifier.trdizinidtrdizinikyoktur
dc.identifier.urihttps://hdl.handle.net/20.500.12587/2948
dc.identifier.volume25en_US
dc.identifier.wosWOS:000168884600012
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakTR-Dizin
dc.language.isotr
dc.publisherScientific Technical Research Council Turkeyen_US
dc.relation.ispartofTurkish Journal Of Veterinary & Animal Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectStrobilocercus fasciolarisen_US
dc.subjectmiceen_US
dc.subjectalbendazoleen_US
dc.subjectpraziquantelen_US
dc.titleThe effect of albendazole and praziquantel on Strobilocercus fasciolaris in experimentally infected miceen_US
dc.typeArticle

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
863b488a-e20d-410e-a6ed-4777dfbf2855.pdf
Size:
67.13 KB
Format:
Adobe Portable Document Format
Description:
Tam metin/Full text
Download

Collections

WOS İndeksli Yayınlar Koleksiyonu
Makale Koleksiyonu
TR-Dizin İndeksli Yayınlar Koleksiyonu

We collect and process your personal information for the following purposes: Authentication, Preferences, Acknowledgement and Statistics.
To learn more, please read our privacy policy.

Customize