The relationship between orthostatic differences in arterial blood pressure and autonomic tone: gender variability

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dc.contributor.authorDogru, Tolga
dc.contributor.authorGunaydin, Serdar
dc.contributor.authorSimsek, Vedat
dc.contributor.authorTulmac, Murat
dc.contributor.authorTireli, Emine
dc.date.accessioned2025-01-21T16:55:14Z
dc.date.available2025-01-21T16:55:14Z
dc.date.issued2007
dc.departmentKırıkkale Üniversitesi
dc.description.abstractObjectives: The differences in orthostatic blood pressure result from dynamic changes in the sympathovagal balance. We studied sex-related variations in autonomic tone regulation. Study design: The study included 237 individuals (114 males, 123 females) who were asymptomatic and had no abnormal laboratory or physical findings. The mean age was 47 years (range 20 to 79 years) for men, and 39 years (range 20 to 71 years) for women. All the participants were subjected to a careful history taking, physical examination, routine biochemical examinations, electrocardiographic recording, 24-hour Holter monitoring, and orthostatic tests. Results: In heart rate variability analysis, parasympathetic tone parameters, in particular the high frequency (HF) component was significantly high in females, whereas sympathetic tone parameters, in particular the low frequency (LF)/HF ratio was significantly high in males (p< 0.001). The normalized LF component in males showed positive correlations with systolic (r= 0.308, p= 0.001) and diastolic (r= 0.301, p= 0.002) blood pressures during the rapid stand test; this correlation was not seen in females. Blood pressures obtained in the second minute of the rapid supine test following the stand test were in positive correlation with the LF/HF ratio in both sexes. In males, variations in systolic and diastolic blood pressures during rest, stand, and supine positions were primarily influenced by the LF component and HF component, respectively. In females, variations in systolic blood pressure during the three positions were not correlated with autonomic tone components, but variations in diastolic blood pressure were primarily affected by the LF/HF ratio. Conclusion: Autonomic system works through varying priorities in both sexes and this causes sex-related differences in orthostatic tolerance.
dc.identifier.endpage77
dc.identifier.issn1016-5169
dc.identifier.issue2
dc.identifier.scopus2-s2.0-39749156955
dc.identifier.scopusqualityQ3
dc.identifier.startpage69
dc.identifier.urihttps://hdl.handle.net/20.500.12587/25734
dc.identifier.volume35
dc.identifier.wosWOS:000421390400001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isotr
dc.publisherAves
dc.relation.ispartofTurk Kardiyoloji Dernegi Arsivi-Archives of The Turkish Society of Cardiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241229
dc.subjectAutonomic nervous system; blood pressure; heart rate; posture/physiology; sex characteristics
dc.titleThe relationship between orthostatic differences in arterial blood pressure and autonomic tone: gender variability
dc.title.alternativeArteryel kan basincindaki ortostatik de?işikliklerin otonomik tonus ile ilişkisi: Cinsiyetle ilgili farkliliklar
dc.typeArticle

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