Respiratory findings in gun factory workers exposed to solvents

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dc.contributor.authorÇakmak, Aytül
dc.contributor.authorEkici, Aydanur
dc.contributor.authorEkici, Mehmet
dc.contributor.authorArslan, Mesut
dc.contributor.authorİteginli, Ahmet
dc.contributor.authorKurtipek, Ercan
dc.contributor.authorKara, Türkan
dc.date.accessioned2020-06-25T15:13:26Z
dc.date.available2020-06-25T15:13:26Z
dc.date.issued2004
dc.departmentKırıkkale Üniversitesi
dc.description.abstractObjective: Gun factory workers are exposed to many solvents (toluene, acetone, butanol, xylene, benzene, trichloroethylene). We investigated whether chronic exposure to solvents had adverse effect on respiratory system. Material and methods: The workers were questionnaired by modified Medical Research Council's respiratory questionnaire before morning start shift. Then physical examination and measurement of pulmonary functions by portable dry rolling spirometer were performed. The study group consisted of 1091 gun factory workers. The workers were grouped according to their smoking habits (smokers, [exposed n: 353 vs. unexposed n: 339] and non-smokers [exposed n: 58 vs. unexposed n: 341]). Asthma-related symptoms were defined as either definite asthma, probable asthma, and possible asthma. Results: In non-smokers, the report of asthma-related symptoms was more prevalent in exposed workers than unexposed (39.7% vs. 21.7% OR 2.4[l.3-4.3], respectively P=0.003). In smokers, the report of asthma-related symptoms was more common in exposed group than unexposed (50.7% vs. 42.5% OR 1.4[l.0-1.9], respectively P=0.03). Logistic regression analysis showed that smoking (OR 2.8 [2.0-3.8] P=0.00001) and exposure to solvents (OR 1.4[l.1-1.9] P=0.01) were independent risk factors for asthma-related symptoms, after adjusting for age. Logistic regression analysis identified that smoking (OR 3.3[2.3-4.6] P=0.00001) was independent risk factors for chronic bronchitis. Multiple linear regression analysis of lung-function parameters (% forced expiratory volume (FEV1), FEV1/forced vital capacity, FEF25-75) indicated significant effects of smoking. Conclusion: Present study indicated significant effects of smoking and exposure to solvents, with the smoking effect being the most important on asthma-related symptoms of gun factory workers. © 2003 Elsevier Ltd. All rights reserved.en_US
dc.identifier.citationCakmak, A., Ekici, A., Ekici, M., Arslan, M., Iteginli, A., Kurtipek, E., & Kara, T. (2004). Respiratory findings in gun factory workers exposed to solvents. Respiratory medicine, 98(1), 52–56. https://doi.org/10.1016/j.rmed.2003.08.006en_US
dc.identifier.doi10.1016/j.rmed.2003.08.006
dc.identifier.endpage56en_US
dc.identifier.issn09546111
dc.identifier.issue1en_US
dc.identifier.pmid14959814
dc.identifier.scopus2-s2.0-0345874723
dc.identifier.scopusqualityQ1
dc.identifier.startpage52en_US
dc.identifier.urihttps://doi.org/10.1016/j.rmed.2003.08.006
dc.identifier.urihttps://hdl.handle.net/20.500.12587/1797
dc.identifier.volume98en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherW.B. Saunders Ltden_US
dc.relation.ispartofRespiratory Medicine
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAsthma-related symptomsen_US
dc.subjectExposureen_US
dc.subjectSolventsen_US
dc.titleRespiratory findings in gun factory workers exposed to solventsen_US
dc.typeArticle

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