Effect of azithromycin on the severity of bronchial hyperresponsiveness in patients with mild asthma

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dc.contributor.authorEkici, A.
dc.contributor.authorEkici, M.
dc.contributor.authorErdemoğlu, A.K.
dc.date.accessioned2020-06-25T17:35:10Z
dc.date.available2020-06-25T17:35:10Z
dc.date.issued2002
dc.departmentKırıkkale Üniversitesi
dc.description.abstractThe effect of azithromycin on bronchial hyperresponsiveness was measured in a group of 11 patients with mild asthma. Azithromycin 250 mg orally was administered intermittently to all the patients twice a week for eight weeks. The only other treatment was inhaled beta2 agonist, when required. A histamine inhalation test was performed at the beginning and at the fourth and the eighth week of the study. The mean PC20 values increased significantly over the initial value at the eighth week after the administration of azithromycin (p < 0.05) but mean values for FEV1 and FEV1 percent predicted did not differ significantly. These results suggested that eight weeks of intermittent, low-dose administration of azithromycin in patients with mild asthma might reduce the severity of bronchial hyperresponsiveness.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1081/JAS-120002199
dc.identifier.endpage185en_US
dc.identifier.issn0277-0903
dc.identifier.issn1532-4303
dc.identifier.issue2en_US
dc.identifier.pmid11990233
dc.identifier.scopus2-s2.0-0036242542
dc.identifier.scopusqualityQ2
dc.identifier.startpage181en_US
dc.identifier.urihttps://doi.org/10.1081/JAS-120002199
dc.identifier.urihttps://hdl.handle.net/20.500.12587/3042
dc.identifier.volume39en_US
dc.identifier.wosWOS:000175213200010
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofJournal Of Asthma
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectbronchial asthmaen_US
dc.subjectbronchial hyperresponsivenessen_US
dc.subjectazithromycinen_US
dc.subjectmacrolidesen_US
dc.subjecthistamineen_US
dc.titleEffect of azithromycin on the severity of bronchial hyperresponsiveness in patients with mild asthmaen_US
dc.typeArticle

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