Acute Kidney Injury in Very Preterm Infants: A Cohort Study in a Level III NICU

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dc.authoridAliefendioglu, Didem/0000-0001-6314-3461
dc.authoridÇelikel Acar, Banu/0000-0002-1808-3655
dc.authoridTandircioglu, Ümit Ayşe/0000-0002-1743-8194
dc.contributor.authorGüzoğlu, Nilüfer
dc.contributor.authorTandircioglu, Ümit Ayşe
dc.contributor.authorBulut, Aye
dc.contributor.authorAcar, Banu Çelikel
dc.contributor.authorAliefendioglu, Didem
dc.date.accessioned2025-01-21T16:33:59Z
dc.date.available2025-01-21T16:33:59Z
dc.date.issued2024
dc.departmentKırıkkale Üniversitesi
dc.description.abstractBACKGROUND/AIMS: Acute kidney injury (AKI) is not rare among preterm infants in neonatal intensive care units (NICU). It raises mortality and morbidity in NICUs and also chronic kidney disease in the long term. The aim of this study was to define the incidence of clinical characteristics and the course of AKI in very preterm infants. MATERIALS AND METHODS: A retrospective cohort study was conducted in a level III NICU in a university hospital. All very preterm infants born in the same hospital during the study period were included in this study. Patient data were taken from the medical records. AKI diagnosis was made using the neonatal-modified Kidney Disease Improving Global Outcomes (KDIGO) criteria. RESULTS: AKI was diagnosed in 20 very preterm infants (42%). The median time of AKI diagnosis was 4.5 days of life (between 2-12 days). While there were 8 infants with AKI when the diagnosis was made based on the serum creatinine (Cr) level being over 1.5, the diagnosis of AKI increased to 20 with the use of the KDIGO criteria. Need for resuscitation in the birth room, patent ductus arteriosus, the number of cases of apnea, desaturation episodes, sepsis, hypotension, inotropic support, and sepsis rates were significantly higher in the AKI group. Days hospitalized among survivors were longer and mortality was higher in the AKI group than in the non-AKI group (p=0.042, p<0.0001 respectively). CONCLUSION: The neonatal KDIGO criteria are beneficial and also informative in diagnosing and staging AKI. Close follow-up of urine output and Cr levels especially in the first days is essential in very preterm infants.
dc.identifier.doi10.4274/cjms.2024.2023-77
dc.identifier.endpage87
dc.identifier.issn2149-7893
dc.identifier.issn2536-507X
dc.identifier.issue2
dc.identifier.startpage84
dc.identifier.trdizinid1252199
dc.identifier.urihttps://doi.org/10.4274/cjms.2024.2023-77
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay1252199
dc.identifier.urihttps://hdl.handle.net/20.500.12587/23890
dc.identifier.volume9
dc.identifier.wosWOS:001229463400006
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherGalenos Publ House
dc.relation.ispartofCyprus Journal of Medical Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241229
dc.subjectAcute kidney injury; preterm; creatinine
dc.titleAcute Kidney Injury in Very Preterm Infants: A Cohort Study in a Level III NICU
dc.typeArticle

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