Blood Chromium-Cobalt Levels In Patients After Total Knee Arthroplasty And Their Effect On The Retinal Nerve Fiber Layer And Macular Ganglion Cell Complex

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dc.contributor.authorOgurel, Tevfik
dc.contributor.authorSerbest, Sancar
dc.contributor.authorOgurel, Reyhan
dc.contributor.authorTiftikci, Ugur
dc.contributor.authorOlmez, Yasar
dc.date.accessioned2021-01-14T18:10:35Z
dc.date.available2021-01-14T18:10:35Z
dc.date.issued2020
dc.departmentKKÜ
dc.description.abstractPurpose: To study blood cobalt (Co) and chromium (Cr) levels in patients who have undergone total knee arthroplasty and their effect on the retinal nerve fiber layer and macular ganglion cell complex. Methods: One hundred patients who had undergone total knee arthroplasty and 50 healthy individuals who had no implants were included in the study. The patients were separated into two groups based on how long ago the prosthesis had been implanted (Group 1: 1 to 5 years; Group 2: 5 to 10 years). After a complete ophthalmological examination, retinal nerve fiber layer and macular ganglion cell complex of the patients were evaluated with optical coherence tomography, performed on dilated pupils. To assess the metal ion levels of the patients, venous blood samples were drawn from each patient. Results: The mean age of the patients was 64.72 +/- 6.26 years in Group 1, 67.80 +/- 8.07 years in Group 2, and 63.42 +/- 7.90 years in the control group. In the comparison of age and sex, there were no statistically significant differences between the groups and the control group. Co and Cr levels were statistically higher in Group 1 and Group 2 compared with the control group (P < 0.001). Mean retinal nerve fiber layer thicknesses and mean macular ganglion cell complex thicknesses in Group 1 and Group 2 were statistically lower than in the control group. Conclusion: Levels of Co and Cr are higher in patients who undergone total knee arthroplasty than healthy subjects, and these higher levels were associated with changes in the retinal nerve fiber layer and macular ganglion cell complex.en_US
dc.description.sponsorshipKirikkale University Scientific Research Projects Coordination Unit, Adiyaman Besni State Hospital, Adiyaman,Turkeyen_US
dc.description.sponsorshipKirikkale University Scientific Research Projects Coordination Unit, Adiyaman Besni State Hospital, Adiyaman,Turkey, supported this studyen_US
dc.identifier.citationBu makale açık erişimli değildir.en_US
dc.identifier.doi10.1097/IAE.0000000000002535
dc.identifier.endpage1206en_US
dc.identifier.issn0275-004X
dc.identifier.issn1539-2864
dc.identifier.issue6en_US
dc.identifier.pmid31021899
dc.identifier.scopus2-s2.0-85079288920
dc.identifier.scopusqualityQ1
dc.identifier.startpage1200en_US
dc.identifier.urihttps://doi.org/10.1097/IAE.0000000000002535
dc.identifier.urihttps://hdl.handle.net/20.500.12587/12688
dc.identifier.volume40en_US
dc.identifier.wosWOS:000539255800030
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherLIPPINCOTT WILLIAMS & WILKINSen_US
dc.relation.ispartofRETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectcobalten_US
dc.subjectchromiumen_US
dc.subjecttotal knee arthroplastyen_US
dc.subjectRNFLen_US
dc.subjectGCCen_US
dc.titleBlood Chromium-Cobalt Levels In Patients After Total Knee Arthroplasty And Their Effect On The Retinal Nerve Fiber Layer And Macular Ganglion Cell Complexen_US
dc.typeArticle

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