Subjective audiological tests and transient evoked otoacoustic emissions in patients with rheumatoid arthritis: analysis of the factors affecting hearing levels

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dc.contributor.authorDikici, Oguzhan
dc.contributor.authorMuluk, Nuray Bayar
dc.contributor.authorTosun, Aliye Kapukiran
dc.contributor.authorUnlusoy, Ihsan
dc.date.accessioned2020-06-25T17:48:10Z
dc.date.available2020-06-25T17:48:10Z
dc.date.issued2009
dc.departmentKırıkkale Üniversitesi
dc.description.abstractWe investigated hearing functions in patients with rheumatoid arthritis (RA) using audiological tests and transient evoked otoacoustic emissions (TEOAEs). The study group consisted of 20 adult patients with RA (7 males, 13 females); 20 adult healthy subjects without RA (7 males, 13 females) were recruited as controls. All patients were evaluated by pure tone audiometry, high frequency audiometry, tympanometry and TEOAEs. There were no statistical differences between the study and control groups with respect to the pure tone and high frequency audiometries. TEOAE results of 1.0-2.0 kHz % and of 1.5 and 3.0 kHz amplitude values were significantly lower, and ipsilateral stapes reflex threshold value at 1.0 kHz was significantly higher in the study group when compared to respective values in the control group. In elderly patients and those with longer disease duration, RA nodules and higher methotrexate cumulative doses, hearing thresholds increased and TEOAE values decreased. In active stage of the disease, hearing thresholds diminished and in higher Brinkman Index values, TEOAE values decreased. Compliance values decreased in patients with higher Ritchie Articular Index, C-reactive protein, erythrocyte sedimentation rate and platelet counts, and longer disease duration. Sensorineural hearing loss is generally observed in patients with RA, and this condition may be detected by TEOAEs in an early period of the disease. Inflammation during the active stage of the disease and the subsequent fibrosis may cause conductive hearing loss of varying degrees. In those patients detected as having initiation of TEOAE decrease, vasodilator treatment and antioxidant drugs may be useful in protecting the inner ear.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1007/s00405-009-0975-y
dc.identifier.endpage1726en_US
dc.identifier.issn0937-4477
dc.identifier.issn1434-4726
dc.identifier.issue11en_US
dc.identifier.pmid19360433
dc.identifier.scopus2-s2.0-77449085001
dc.identifier.scopusqualityQ1
dc.identifier.startpage1719en_US
dc.identifier.urihttps://doi.org/10.1007/s00405-009-0975-y
dc.identifier.urihttps://hdl.handle.net/20.500.12587/4343
dc.identifier.volume266en_US
dc.identifier.wosWOS:000270437200007
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringeren_US
dc.relation.ispartofEuropean Archives Of Oto-Rhino-Laryngology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectRheumatoid arthritis (RA)en_US
dc.subjectHearing levelsen_US
dc.subjectPure tone audiometryen_US
dc.subjectHigh frequency audiometryen_US
dc.subjectTransient evoked otoacoustic emissions (TEOAEs)en_US
dc.titleSubjective audiological tests and transient evoked otoacoustic emissions in patients with rheumatoid arthritis: analysis of the factors affecting hearing levelsen_US
dc.typeArticle

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