IgE allergy diagnostics and other relevant tests in allergy, a World Allergy Organization position paper

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dc.contributor.authorAnsotegui, Ignacio J.
dc.contributor.authorMelioli, Giovanni
dc.contributor.authorCanonica, Giorgio Walter
dc.contributor.authorCaraballo, Luis
dc.contributor.authorVilla, Elisa
dc.contributor.authorEbisawa, Motohiro
dc.contributor.authorZuberbier, Torsten
dc.date.accessioned2020-06-25T18:34:55Z
dc.date.available2020-06-25T18:34:55Z
dc.date.issued2020
dc.departmentKırıkkale Üniversitesi
dc.descriptionZuberbier, Torsten/0000-0002-1466-8875
dc.description.abstractCurrently, testing for immunoglobulin E (IgE) sensitization is the cornerstone of diagnostic evaluation in suspected allergic conditions. This review provides a thorough and updated critical appraisal of the most frequently used diagnostic tests, both in vivo and in vitro. It discusses skin tests, challenges, and serological and cellular in vitro tests, and provides an overview of indications, advantages and disadvantages of each in conditions such as respiratory, food, venom, drug, and occupational allergy. Skin prick testing remains the first line approach in most instances; the added value of serum specific IgE to whole allergen extracts or components, as well as the role of basophil activation tests, is evaluated. Unproven, non-validated, diagnostic tests are also discussed. Throughout the review, the reader must bear in mind the relevance of differentiating between sensitization and allergy; the latter entails not only allergic sensitization, but also clinically relevant symptoms triggered by the culprit allergen.en_US
dc.description.sponsorshipWAO Board of Directorsen_US
dc.description.sponsorshipThe authors wish to thank the allergy societies from the membership of the World Allergy Organization who provided critical review of the draft and the WAO Board of Directors for supporting this work.en_US
dc.identifier.citationAnsotegui, I., Melioli, G., Canonica, G., Caraballo, L., Villa, E., Ebisawa, M., … Oppenheimer, J. (2020). IgE allergy diagnostics and other relevant tests in allergy a World Allergy Organization position paper. World Allergy Organization Journal, 13, 0–0.en_US
dc.identifier.doi10.1016/j.waojou.2019.100080
dc.identifier.issn1939-4551
dc.identifier.issue2en_US
dc.identifier.pmid32128023
dc.identifier.scopus2-s2.0-85079872551
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1016/j.waojou.2019.100080
dc.identifier.urihttps://hdl.handle.net/20.500.12587/8071
dc.identifier.volume13en_US
dc.identifier.wosWOS:000523267300003
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevieren_US
dc.relation.ispartofWorld Allergy Organization Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectIgEen_US
dc.subjectAllergyen_US
dc.subjectIn vitro testsen_US
dc.subjectSkin testsen_US
dc.subjectDiagnostic strategiesen_US
dc.titleIgE allergy diagnostics and other relevant tests in allergy, a World Allergy Organization position paperen_US
dc.typeArticle

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