The Importance of Micronutrients in Cystic Fibrosis

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dc.authoridYabanci, Nurcan/0000-0003-1233-246X
dc.contributor.authorDurmaz, Sevinc Eser
dc.contributor.authorYabanci, Nurcan
dc.date.accessioned2025-01-21T16:45:35Z
dc.date.available2025-01-21T16:45:35Z
dc.date.issued2021
dc.departmentKırıkkale Üniversitesi
dc.description.abstractCystic fibrosis is an inherited disease with an autosomal recessive transition, characterized by a clinically progressive lung disease, which is caused by mutations occurring in the transmembrane conductance regulator (KFTR) gene, affecting all cells with epithelial tissue, especially the respiratory system. Approximately 90% of individuals experience pancreatic insufficiency and malabsorption. Chronic infection and increased energy requirement in the pathogenesis of the disease, together with malabsorption, pose a risk for malnutrition. Decreased absorption of micronutrients due to malabsorptions, increase in the requirement, inadequate intake, and as a result, poor prognosis of the disease leads to decreased quality of life and duration. Nutritional status changes should be determined in cystic fibrosis and early and appropriate nutritional interventions should be made. It is recommended to follow the growth and nutritional status throughout life in cystic fibrosis. Optimal nutritional status should be provided in the early stages of life, under the control of a dietitian, with pancreatic enzyme replacement therapy (PERT), hydration and electrolyte balance. Although optimal nutrition in cystic fibrosis is effective in diet and micronutrient intake with proper cooking methods, deficiency of micronutrients in these patients can not be prevented. In this case, taking into account the recommendations of the guidelines along with optimal nutrition, vitamin-mineral supplements in accordance with the needs and biochemical values of individuals are needed.
dc.identifier.doi10.4274/jcp.2021.0018
dc.identifier.endpage134
dc.identifier.issn1304-9054
dc.identifier.issn1308-6308
dc.identifier.issue1
dc.identifier.scopus2-s2.0-85104637519
dc.identifier.scopusqualityQ4
dc.identifier.startpage127
dc.identifier.urihttps://doi.org/10.4274/jcp.2021.0018
dc.identifier.urihttps://hdl.handle.net/20.500.12587/25680
dc.identifier.volume19
dc.identifier.wosWOS:000735332200018
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isotr
dc.publisherBursa Uludag Univ
dc.relation.ispartofGuncel Pediatri-Journal of Current Pediatrics
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241229
dc.subjectCystic fibrosis; malabsorption; micronutrients; nutrition
dc.titleThe Importance of Micronutrients in Cystic Fibrosis
dc.title.alternativeKistik fibroziste mikrobesin ögelerinin önemi
dc.typeReview Article

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