Atrophic and regenerative changes in rabbit mimic muscles after lidocaine and bupivacaine application
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Tarih
2003
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Destruction and denervation atrophy in skeletal muscles caused by the injection of local anaesthetics was investigated by injecting lidocaine or bupivacaine around the rabbit facial nerve to produce facial paralysis. Animals were then sacrificed at 2, 4, 6, and 8 weeks post-injection, and changes in mimic muscle tissue were assessed at each stage by light microscopy and electron microscopy. Atrophic changes were observed at 2-6 weeks after injection, and regeneration started at 6-8 weeks. Compared to bupivacaine, lidocaine caused more dramatic atrophic changes and was associated with slower muscle regeneration.
Açıklama
Anahtar Kelimeler
Kaynak
Journal of Veterinary Medicine Series C: Anatomia Histologia Embryologia
WoS Q Değeri
Scopus Q Değeri
Q2
Cilt
32
Sayı
1
