Atrophic and regenerative changes in rabbit mimic muscles after lidocaine and bupivacaine application

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dc.contributor.authorÇalgüner E.
dc.contributor.authorGözil R.
dc.contributor.authorErdoğan D.
dc.contributor.authorKurt I.
dc.contributor.authorKeskil S.
dc.contributor.authorElmas Ç.
dc.contributor.authorSabuncuoğlu H.
dc.date.accessioned2020-06-25T15:13:19Z
dc.date.available2020-06-25T15:13:19Z
dc.date.issued2003
dc.departmentKırıkkale Üniversitesi
dc.description.abstractDestruction and denervation atrophy in skeletal muscles caused by the injection of local anaesthetics was investigated by injecting lidocaine or bupivacaine around the rabbit facial nerve to produce facial paralysis. Animals were then sacrificed at 2, 4, 6, and 8 weeks post-injection, and changes in mimic muscle tissue were assessed at each stage by light microscopy and electron microscopy. Atrophic changes were observed at 2-6 weeks after injection, and regeneration started at 6-8 weeks. Compared to bupivacaine, lidocaine caused more dramatic atrophic changes and was associated with slower muscle regeneration.en_US
dc.identifier.doi10.1046/j.1439-0264.2003.00439.x
dc.identifier.endpage59en_US
dc.identifier.issn03402096
dc.identifier.issue1en_US
dc.identifier.pmid12733274
dc.identifier.scopus2-s2.0-0141924776
dc.identifier.scopusqualityQ2
dc.identifier.startpage54en_US
dc.identifier.urihttps://doi.org/10.1046/j.1439-0264.2003.00439.x
dc.identifier.urihttps://hdl.handle.net/20.500.12587/1734
dc.identifier.volume32en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.relation.ispartofJournal of Veterinary Medicine Series C: Anatomia Histologia Embryologia
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleAtrophic and regenerative changes in rabbit mimic muscles after lidocaine and bupivacaine applicationen_US
dc.typeArticle

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