Evaluation of peripheral olfactory pathways in chronic autoimmune thyroiditis

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dc.authoridINAL, MIKAIL/0000-0003-0642-7913
dc.contributor.authorInal, Mikail
dc.contributor.authorAsal, Nese
dc.contributor.authorKarahan, Irfan
dc.contributor.authorGungunes, Askin
dc.contributor.authorDurmaz, Senay Arikan
dc.date.accessioned2025-01-21T16:40:40Z
dc.date.available2025-01-21T16:40:40Z
dc.date.issued2022
dc.departmentKırıkkale Üniversitesi
dc.description.abstractPurpose In this study, we aimed to radiologically evaluate the olfactory bulb (OB) volume and olfactory sulcus (OS) depth of adult patients diagnosed with chronic autoimmune thyroiditis. Methods Sixty-eight patients over 18 years of age with Hashimoto's thyroiditis and 66 healthy controls with normal thyroid function tests were included in the study. OB volume and OS depth measurements were performed using cranial magnetic resonance imaging (MRI) obtained from coronal T2-weighted images. The relationship between thyroid function tests, autoantibodies, and measurements of the OB and OS were evaluated. Results The right and left OB volumes were significantly lower in the patients with Hashimoto's thyroiditis than in the control group (p < 0.05). No significant difference was found between the patient and control groups in terms of OS depth (p > 0.05). There were significantly negative correlations among TSH, thyroid antibodies, and the bilateral OB volume measurements. In the Bonferroni post hoc analysis, when people with euthyroid Hashimoto's thyroiditis and the control group were compared, there was no statistically significant difference between bilateral OB volumes and thyroid function tests. Conclusion Diminished bilateral OB volumes were found in our patients with chronic autoimmune thyroiditis. Interestingly, the OB volumes were not affected in patients with euthyroid Hashimoto's thyroiditis. When a decrease in OB volume is detected on MRI, it should be kept in mind that odor dysfunction in hypothyroid patients with Hashimoto's thyroiditis may occur and patients should be clinically evaluated.
dc.identifier.doi10.1007/s00405-022-07373-z
dc.identifier.endpage4532
dc.identifier.issn0937-4477
dc.identifier.issn1434-4726
dc.identifier.issue9
dc.identifier.pmid35434779
dc.identifier.scopus2-s2.0-85128218326
dc.identifier.scopusqualityQ1
dc.identifier.startpage4525
dc.identifier.urihttps://doi.org/10.1007/s00405-022-07373-z
dc.identifier.urihttps://hdl.handle.net/20.500.12587/24743
dc.identifier.volume279
dc.identifier.wosWOS:000783084600002
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer
dc.relation.ispartofEuropean Archives of Oto-Rhino-Laryngology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241229
dc.subjectOlfactory bulb volume; Olfactory sulcus depth; Cranial MRI; Hashimoto's thyroiditis
dc.titleEvaluation of peripheral olfactory pathways in chronic autoimmune thyroiditis
dc.typeArticle

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