Effects of vasoconstriction on the acute anterior pituitary hormonal response to head injury

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dc.contributor.authorKeskil, Z.
dc.contributor.authorEvrenkaya, T.
dc.contributor.authorGozil, R.
dc.contributor.authorCalguner, E.
dc.contributor.authorKeskil, S.
dc.date.accessioned2020-06-25T17:35:00Z
dc.date.available2020-06-25T17:35:00Z
dc.date.issued2002
dc.departmentKırıkkale Üniversitesi
dc.description.abstractSince cerebral vasoconstriction alone may impair the hypothalamic and pituitary circulation, we planned to investigate whether the hormonal response to the vasoconstriction that may be induced by the head injury is a significant component of the general acute hormonal response to head injury. Although diffuse adrenocorticotropic hormone immunohistochemical staining of the adenohypophysis of rabbits was observed in the head trauma administered group, only mild positive staining was present in the Endothelin-1 administered group. However, decreased prolactin staining was found in both of the groups. It is postulated that trauma induced vasoconstriction may not be an important manipulating factor in the corticotrophic hormone response to injury, while it may be responsible for the decreased prolactin response. (C) 2002 Elsevier Science Ltd. All rights reserved.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1016/S0143-4179(02)00047-1
dc.identifier.endpage290en_US
dc.identifier.issn0143-4179
dc.identifier.issue4en_US
dc.identifier.pmid12372703
dc.identifier.scopus2-s2.0-0036700725
dc.identifier.scopusqualityQ2
dc.identifier.startpage287en_US
dc.identifier.urihttps://doi.org/10.1016/S0143-4179(02)00047-1
dc.identifier.urihttps://hdl.handle.net/20.500.12587/2987
dc.identifier.volume36en_US
dc.identifier.wosWOS:000178883400008
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherChurchill Livingstoneen_US
dc.relation.ispartofNeuropeptides
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleEffects of vasoconstriction on the acute anterior pituitary hormonal response to head injuryen_US
dc.typeArticle

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