Olfactory dysfunction and oxidative stress in pregnant women with hyperemesis gravidarum

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dc.authoridBAYAR MULUK, NURAY/0000-0003-3602-9289
dc.contributor.authorSimsek, Yavuz
dc.contributor.authorSimsek, Gokce
dc.contributor.authorMuluk, Nuray Bayar
dc.contributor.authorArikan, Osman Kursat
dc.date.accessioned2025-01-21T16:43:02Z
dc.date.available2025-01-21T16:43:02Z
dc.date.issued2021
dc.departmentKırıkkale Üniversitesi
dc.description.abstractPurpose This study aimed to compare the first-trimester pregnancy serum total oxidative status (TOS), total antioxidant status (TAS), and serum estradiol levels as well as the olfactory functions assessed using the brief smell identification test (BSIT) of women with healthy pregnancies and those with hyperemesis gravidarum (HG). Methods In this prospective study, 60 pregnant women in the first trimester of their pregnancies were divided into two groups: 30 pregnant women with HG (study group) and 30 healthy pregnant women (control group). The following parameters were compared in the HG group and the healthy controls: TOS, TAS, serum levels of estradiol (E2), and olfactory function, which was measured using BSIT. Results Both groups were similar in terms of age, gravida, and parity. The mean total smell score was lower in the HG group than the healthy control group (p < 0.05). TOS was significantly higher in the HG group than the control group. TAS was significantly higher in the control group than the HG group (p < 0.05). Conclusion The removal of sharp odors that will trigger the perception of odor in pregnant women with HG can contribute to the effective control of this disease; moreover, adding fetal-safe antioxidants to the treatment can contribute to the effective control of this disease.
dc.description.sponsorshipKirikkale University Scientific Research Projects and Coordination Unit [2014/078]
dc.description.sponsorshipThis work was supported by the Kirikkale University Scientific Research Projects and Coordination Unit (project number 2014/078).
dc.identifier.doi10.1007/s00404-021-05998-9
dc.identifier.endpage661
dc.identifier.issn0932-0067
dc.identifier.issn1432-0711
dc.identifier.issue3
dc.identifier.pmid33591381
dc.identifier.scopus2-s2.0-85100918508
dc.identifier.scopusqualityQ2
dc.identifier.startpage657
dc.identifier.urihttps://doi.org/10.1007/s00404-021-05998-9
dc.identifier.urihttps://hdl.handle.net/20.500.12587/25190
dc.identifier.volume304
dc.identifier.wosWOS:000618609500001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer Heidelberg
dc.relation.ispartofArchives of Gynecology and Obstetrics
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241229
dc.subjectHyperemesis gravidarum (HG); Total oxidative status (TOS); Total antioxidant status (TAS); Brief smell identification test (BSIT)
dc.titleOlfactory dysfunction and oxidative stress in pregnant women with hyperemesis gravidarum
dc.typeArticle

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