Blink reflex in hypothyroidism

dc.contributor.authorNazliel, Bijen
dc.contributor.authorYilmaz, Murat
dc.contributor.authorGökçe, Mustafa
dc.contributor.authorYetkin, İlhan
dc.contributor.authorBaysal, Ali İhsan
dc.date.accessioned2020-06-25T17:43:48Z
dc.date.available2020-06-25T17:43:48Z
dc.date.issued2007
dc.description.abstractAim: The aim of the present study was to evaluate the usefulness of the blink reflex as a method for obtaining an early diagnosis of central nervous system dysfunction in hypothyroid patients who do not have signs or symptoms of nervous system dysfunction. Materials and Methods: Forty-two patients (3 males, 39 females), mean age 40 (+/- 11), with newly diagnosed primary hypothyroidism and 30 healthy control subjects were included in the study. In all patients, the cause of hypothyroidism was chronic autoimmune thyroiditis. For blink reflex testing, subjects lay supine on a bed in a warm room with eyes gently closed. Recordings were performed with an EMG machine (Nihon Kohden/Neuropack), with a filter setting of 20 Hz to 10 kHz, using an analysis time of 50 ms. Recordings were performed with surface recording electrodes (Dantec 13K60, Copenhagen, Denmark). Results: Second ipsilateral response (R2Y) and second contralateral response (R2C) latencies in hypothyroidism were prolonged relative to controls, and the differences were statistically significant (P < 0.001 and P < 0.001, respectively). Latency of R1, R2Y, and R2C did not correlate with free T3, free T4, or TSH values in the hypothyroid group. Conclusion: The finding of abnormal blink reflex responses in hypothyroid individuals raises the notion that they may be useful in detecting early changes and in the follow-up of the patients with the disorder.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1097/TEN.0b013e31806b8a0e
dc.identifier.endpage147en_US
dc.identifier.issn1051-2144
dc.identifier.issn1539-9192
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-34249107036
dc.identifier.scopusqualityN/A
dc.identifier.startpage144en_US
dc.identifier.urihttps://doi.org10.1097/TEN.0b013e31806b8a0e
dc.identifier.urihttps://hdl.handle.net/20.500.12587/3905
dc.identifier.volume17en_US
dc.identifier.wosWOS:000246828800003
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofEndocrinologist
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectblink reflexen_US
dc.subjecthypothyroiden_US
dc.subjectelectrophysiological evaluationen_US
dc.subjectcentral nervous system dysfunctionen_US
dc.subjectponsen_US
dc.titleBlink reflex in hypothyroidismen_US
dc.typeArticle

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