The efficacy and safety of gabapentin in carpal tunnel patients: Open label trial

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dc.contributor.authorErdemoğlu, A. Kemal
dc.date.accessioned2020-06-25T17:48:28Z
dc.date.available2020-06-25T17:48:28Z
dc.date.issued2009
dc.departmentKırıkkale Üniversitesi
dc.description.abstractBackground: Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy caused by median nerve compression at the wrist. It results in loss of considerable man days and the effectiveness the various treatment modalities are still debated. Aim: To study the efficacy of gabapentin in patients with CTS. The study aim is to investigate the efficacy of gabapentin in patients with CTS patients who were refractory to the other conservative measures or unwilling for the surgical procedure. Materials and Methods: Forty one patients diagnosed as idiopathic CTS were included in the study. Patients were assessed with symptom severity scale (SSS) and functional status scale (FSS) scores of Boston Carpal Tunnel Questionnaire (BCTQ) before and at 1, 3, and 6 months of the treatment. Response to therapy was determined by using SSS and FSS scores of BCTQ. Results: The median dosage of gabapentin was 1800 mg/daily. Side effects were mild and transient. There was a statistically significant difference in both symptom SSS and FSS scores between before and after treatment in patient groups at the end of six months (P < 0.001). According to grading the changes in subscales of BCTQ, of 41 patients, 34.1 and 29.3 had a >= 40 decrease in SSS and FSS, respectively. Conclusion: Gabapentin was found to be partially effective and safe in symptomatic treatment of CTS patients.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.4103/0028-3886.53287
dc.identifier.endpage303en_US
dc.identifier.issn0028-3886
dc.identifier.issue3en_US
dc.identifier.pmid19587471
dc.identifier.scopus2-s2.0-67651171442
dc.identifier.scopusqualityQ3
dc.identifier.startpage300en_US
dc.identifier.urihttps://doi.org/10.4103/0028-3886.53287
dc.identifier.urihttps://hdl.handle.net/20.500.12587/4460
dc.identifier.volume57en_US
dc.identifier.wosWOS:000267981400014
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherMedknow Publicationsen_US
dc.relation.ispartofNeurology India
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCarpal tunnel syndromeen_US
dc.subjectgabapentinen_US
dc.subjectboston carpal tunnel questionnaireen_US
dc.titleThe efficacy and safety of gabapentin in carpal tunnel patients: Open label trialen_US
dc.typeArticle

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