Use of intranasal corticosteroids in adenotonsillar hypertrophy

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dc.contributor.authorSakarya, E. U.
dc.contributor.authorMuluk, N. Bayar
dc.contributor.authorSakalar, E. G.
dc.contributor.authorSenturk, M.
dc.contributor.authorAricigil, M.
dc.contributor.authorBafaqeeh, S. A.
dc.contributor.authorCingi, C.
dc.date.accessioned2020-06-25T18:23:02Z
dc.date.available2020-06-25T18:23:02Z
dc.date.issued2017
dc.departmentKırıkkale Üniversitesi
dc.description.abstractObjectives: This review examined the efficacy of intranasal corticosteroids for improving adenotonsillar hypertrophy. Method: The related literature was searched using PubMed and Proquest Central databases. Results: Adenotonsillar hypertrophy causes mouth breathing, nasal congestion, hyponasal speech, snoring, obstructive sleep apnoea, chronic sinusitis and recurrent otitis media. Adenoidal hypertrophy results in the obstruction of nasal passages and Eustachian tubes, and blocks the clearance of nasal mucus. Adenotonsillar hypertrophy and obstructive sleep apnoea are associated with increased expression of various mediators of inflammatory responses in the tonsils, and respond to anti-inflammatory agents such as corticosteroids. Topical nasal steroids most likely affect the anatomical component by decreasing inspiratory upper airway resistance at the nasal, adenoidal or tonsillar levels. Corticosteroids, by their lympholytic or anti-inflammatory effects, might reduce adenotonsillar hypertrophy. Intranasal corticosteroids reduce cellular proliferation and the production of pro-inflammatory cytokines in a tonsil and adenoid mixed-cell culture system. Conclusion: Intranasal corticosteroids have been used in adenoidal hypertrophy and adenotonsillar hypertrophy patients, decreasing rates of surgery for adenotonsillar hypertrophy.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1017/S0022215117000408
dc.identifier.endpage390en_US
dc.identifier.issn0022-2151
dc.identifier.issn1748-5460
dc.identifier.issue5en_US
dc.identifier.pmid28238295
dc.identifier.scopus2-s2.0-85013873697
dc.identifier.scopusqualityQ2
dc.identifier.startpage384en_US
dc.identifier.urihttps://doi.org/10.1017/S0022215117000408
dc.identifier.urihttps://hdl.handle.net/20.500.12587/6988
dc.identifier.volume131en_US
dc.identifier.wosWOS:000400960200003
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherCambridge Univ Pressen_US
dc.relation.ispartofJournal Of Laryngology And Otology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHypertrophyen_US
dc.subjectAdenoidsen_US
dc.subjectTonsilen_US
dc.subjectSleep Apneaen_US
dc.subjectObstructiveen_US
dc.subjectSteroidsen_US
dc.titleUse of intranasal corticosteroids in adenotonsillar hypertrophyen_US
dc.typeArticle

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