Update on local allergic rhinitis

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dc.contributor.authorAltintoprak, Niyazi
dc.contributor.authorKar, Murat
dc.contributor.authorMuluk, Nuray Bayar
dc.contributor.authorOktemer, Tugba
dc.contributor.authorIpci, Kagan
dc.contributor.authorBirdane, Leman
dc.contributor.authorCingi, Cemal
dc.date.accessioned2020-06-25T18:16:24Z
dc.date.available2020-06-25T18:16:24Z
dc.date.issued2016
dc.departmentKırıkkale Üniversitesi
dc.description.abstractWe here provide an update on the literature regarding local allergic rhinitis (LAR). In reviewing LAR, we have included an updated definition, classifications, mechanisms, comorbidities, and recommendations for diagnosis and treatment for LAR, as well as the defined research areas for future evidence-based studies. LAR is a localised nasal allergic response in the absence of systemic atopy characterised by local production of specific IgE (sIgE) antibodies, a TH2 pattern of mucosal cell infiltration during natural exposure to aeroallergens, and a positive nasal allergen provocation test response, with the release of inflammatory mediators. The localised allergic response of LAR is an important topic for the study of allergies. This review provides an update on the current knowledge of LAR. (C) 2016 Elsevier Ireland Ltd. All rights reserved.en_US
dc.description.sponsorshipContinuing Education and Scientific Research Associationen_US
dc.description.sponsorshipPreparation of this paper, including design and planning, was supported by the Continuing Education and Scientific Research Association.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1016/j.ijporl.2016.06.008
dc.identifier.endpage109en_US
dc.identifier.issn0165-5876
dc.identifier.issn1872-8464
dc.identifier.pmid27368453
dc.identifier.scopus2-s2.0-84973469452
dc.identifier.scopusqualityQ2
dc.identifier.startpage105en_US
dc.identifier.urihttps://doi.org/10.1016/j.ijporl.2016.06.008
dc.identifier.urihttps://hdl.handle.net/20.500.12587/6516
dc.identifier.volume87en_US
dc.identifier.wosWOS:000380082000020
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier Ireland Ltden_US
dc.relation.ispartofInternational Journal Of Pediatric Otorhinolaryngology
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectLocal allergic rhinitisen_US
dc.subjectAbsenceen_US
dc.subjectSystemic atopyen_US
dc.subjectLocal productionen_US
dc.subjectSpecific IgEen_US
dc.subjectAntibodiesen_US
dc.subjectMechanismen_US
dc.titleUpdate on local allergic rhinitisen_US
dc.typeReview Article

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