Evaluating ESWL related alterations in renal pelvis and proximal ureter by analayting of tissue hydroxyproline levels

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dc.contributor.authorFedakar Senyucel M.
dc.contributor.authorBoybeyi O.
dc.contributor.authorKemalAslan M.
dc.contributor.authorSoyer T.
dc.contributor.authorBalci M.
dc.contributor.authorIzzetDemet A.
dc.contributor.authorCakmak M.
dc.date.accessioned2020-06-25T15:17:34Z
dc.date.available2020-06-25T15:17:34Z
dc.date.issued2015
dc.departmentKırıkkale Üniversitesi
dc.description.abstractThe aim of the study is to evaluate extracorporeal shock wave lithotripsy (ESWL) related alterations in renal pelvis and proximal ureter by using histopathological methods and analayting hydroxy-proline levels. Twelve New-Zealand rabbits were allocated into two groups (n=6). Right sites of control group (CG, n=6) were harvested without any intervention. In ESWL group (EG), right kidneys of subjects were exposed to 3000 shock waves (14 kV) by using electro-hydraulic type ESWL device three times. Rabbits in EG were sacrificed on day 7. Tissues were examined histopathologically for presence of edema, inflammation, congestion, hemorrhage, fibrosis, vascularization and biochemically for hydroxyproline concentrations. Histopathologically, tissue edema was increased in renal pelvises and inflammation was increased in ureters in the EG compared to that in the CG (p<0.5). There was no difference in other parameters between the groups (p>0.05). Tissue collagen density did not show any significant difference (p>0.05). There was no difference in the tissue hydroxyl-proline levels of ureter samples (p>0.05). Tissue hydroxyproline levels were significantly higher in EG than CG in renal pelvis (p<0.05). In conclusion, although no major histopathological alteration due to ESWL was detected in renal pelvis and proximal ureter, increased hydroxyproline levels in the renal pelvis can be suggested as a finding of tissue injury in collecting system. © 2015 OMU.en_US
dc.identifier.citationSenyücel, M. F., Türer, Ö. B., Aslan, M. K., Soyer, T., Balcı, M., Demet, A. İ., Kısa, Ü., Başar, M., Çakmak, A. M. (2015). Evaluating ESWL related alterations in renal pelvis and proximal ureter by analayting of tissue hydroxyproline levels. Journal of Experimental and Clinical Medicine, 32(1), 31 - 34.en_US
dc.identifier.doi10.5835/jecm.omu.32.01.006
dc.identifier.endpage34en_US
dc.identifier.issn13094483
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85006575402
dc.identifier.scopusqualityQ4
dc.identifier.startpage31en_US
dc.identifier.trdizinid197406
dc.identifier.urihttps://doi.org/10.5835/jecm.omu.32.01.006
dc.identifier.urihttps://hdl.handle.net/20.500.12587/2428
dc.identifier.volume32en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherOndokuz Mayis Universitesien_US
dc.relation.ispartofJournal of Experimental and Clinical Medicine (Turkey)
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCollecting systemen_US
dc.subjectESWLen_US
dc.subjectHydroxyprolineen_US
dc.subjectRenal pelvisen_US
dc.subjectUreteren_US
dc.titleEvaluating ESWL related alterations in renal pelvis and proximal ureter by analayting of tissue hydroxyproline levelsen_US
dc.typeConference Object

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