Strategic leukofiltration in cardiac surgery
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Tarih
2005
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Systemic inflammatory response syndrome (SIRS) with activation of molecular cascades, cell activation, accumulation of interstitial fluid, organ dysfunction and, occasionally, organ failure is still a commonly recognized consequence of cardiac surgery. SIRS leads to costly complications and several strategies intended to ameliorate the symptoms that have been studied, including leukocyte reduction, using filtration. Although, the body of work suggests that leukoreduction attenuates SIRS, discrepancies remain within the literature. The recent literature is reviewed highlighting the areas where concordance is lacking. In our study, on the basis of indirect indicators of SIRS, platelet function by thromboelastography biomaterial evaluation by light and scanning electron microscopy, we present our conclusions regarding clinical outcomes and the role of leukofiltration. © 2005 Bentham Science Publishers Ltd.
Açıklama
Anahtar Kelimeler
Cardiopulmonary bypass, Coated materials-biocompatible, Leukapheresis, Leukocyte filtration, Reperfusion injury, Surface modifying additives
Kaynak
Current Medicinal Chemistry: Cardiovascular and Hematological Agents
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
3
Sayı
4
Künye
closedAccess
