Strategic leukofiltration in cardiac surgery

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dc.contributor.authorGünaydın, Serdar
dc.contributor.authorMcCusker, Kevin
dc.contributor.authorVijay, V.
dc.date.accessioned2020-06-25T15:13:29Z
dc.date.available2020-06-25T15:13:29Z
dc.date.issued2005
dc.departmentKırıkkale Üniversitesi
dc.description.abstractSystemic inflammatory response syndrome (SIRS) with activation of molecular cascades, cell activation, accumulation of interstitial fluid, organ dysfunction and, occasionally, organ failure is still a commonly recognized consequence of cardiac surgery. SIRS leads to costly complications and several strategies intended to ameliorate the symptoms that have been studied, including leukocyte reduction, using filtration. Although, the body of work suggests that leukoreduction attenuates SIRS, discrepancies remain within the literature. The recent literature is reviewed highlighting the areas where concordance is lacking. In our study, on the basis of indirect indicators of SIRS, platelet function by thromboelastography biomaterial evaluation by light and scanning electron microscopy, we present our conclusions regarding clinical outcomes and the role of leukofiltration. © 2005 Bentham Science Publishers Ltd.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.2174/156801605774322328
dc.identifier.endpage331en_US
dc.identifier.issn15680169
dc.identifier.issue4en_US
dc.identifier.pmid16250863
dc.identifier.scopus2-s2.0-24644454661
dc.identifier.scopusqualityN/A
dc.identifier.startpage323en_US
dc.identifier.urihttps://doi.org/10.2174/156801605774322328
dc.identifier.urihttps://hdl.handle.net/20.500.12587/1816
dc.identifier.volume3en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.relation.ispartofCurrent Medicinal Chemistry: Cardiovascular and Hematological Agents
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCardiopulmonary bypassen_US
dc.subjectCoated materials-biocompatibleen_US
dc.subjectLeukapheresisen_US
dc.subjectLeukocyte filtrationen_US
dc.subjectReperfusion injuryen_US
dc.subjectSurface modifying additivesen_US
dc.titleStrategic leukofiltration in cardiac surgeryen_US
dc.typeReview Article

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