Histomorphometric examination of long-term changes in temporomandibular joints after mandibular lengthening by distraction osteogenesis in rabbits

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dc.contributor.authorMihmanli, Ahmet
dc.contributor.authorDolanmaz, Dogan
dc.contributor.authorTuz, Hakan
dc.contributor.authorPampu, Alper
dc.contributor.authorDonmez, Hasan Huseyin
dc.date.accessioned2020-06-25T18:06:35Z
dc.date.available2020-06-25T18:06:35Z
dc.date.issued2012
dc.departmentKırıkkale Üniversitesi
dc.descriptiondonmez, hasan huseyin/0000-0003-4664-8489
dc.description.abstractObjective. The purpose of this study was to evaluate long-term histomorphometric changes in temporomandibular joints (TMJs) of rabbits after mandibular distraction osteogenesis (DO). Study Design. Twenty-six rabbits were used in this study. Two of them served as control subjects, and the remaining 24 underwent DO procedures in their left mandibular bodies. After a latency period of 5 days, 5 mm lengthening was performed at a rate of 1 mm/d. The rabbits in the experimental group were randomly divided into 4 subgroups and killed after 1, 2, 4, and 6 months. TMJs from both sides were harvested and prepared with hematoxylin and eosin stain for histomorphometric examination under an optical microscope. Results. Compared with control subjects and nondistracted sides, fibrous articular, proliferative, and hypertrophic areas were significantly increased (P < .05) in the first 2 months in distracted sides. The changes were insignificant in the fourth and sixth postoperative months. Conclusion. Unilateral mandibular distraction of 5 mm was found to be well tolerated and no degenerative changes were observed histologically in the rabbit TMJs in the long-term period. (Oral Surg Oral Med Oral Pathol Oral Radiol 2012;113:600-603)en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1016/j.tripleo.2011.04.043
dc.identifier.endpage603en_US
dc.identifier.issn2212-4403
dc.identifier.issn1528-395X
dc.identifier.issue5en_US
dc.identifier.pmid22676985
dc.identifier.scopus2-s2.0-84862527508
dc.identifier.scopusqualityQ1
dc.identifier.startpage600en_US
dc.identifier.urihttps://doi.org/10.1016/j.tripleo.2011.04.043
dc.identifier.urihttps://hdl.handle.net/20.500.12587/5268
dc.identifier.volume113en_US
dc.identifier.wosWOS:000303402200015
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier Science Incen_US
dc.relation.ispartofOral Surgery Oral Medicine Oral Pathology Oral Radiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleHistomorphometric examination of long-term changes in temporomandibular joints after mandibular lengthening by distraction osteogenesis in rabbitsen_US
dc.typeArticle

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