Pancreas and kidney changes in type 2 diabetes patients: The role of diffusion-weighteimaging

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dc.contributor.authorŞahan, Mehmet Hamdi
dc.contributor.authorÖzdemir, Adnan
dc.contributor.authorAsal, Neşe
dc.contributor.authorKaradeniz Bilgili, Yasemin Mirace
dc.contributor.authorDoğan, Adil
dc.contributor.authorGüngüneş, Aşkın
dc.date.accessioned2025-01-21T16:28:11Z
dc.date.available2025-01-21T16:28:11Z
dc.date.issued2021
dc.departmentKırıkkale Üniversitesi
dc.description.abstractBackground/aim: The aim of this study was to compare renal and pancreatic apparent diffusion-coefficient (ADC) values of dipatients and control subjects and to examine their potential association with several diabetes-related clinical parameters. Materials and methods: A total of 80 sex-and age-matched patients were included in the study. Of them, 40 were patients with type 2 diabetes and 40 were nondiabetic participants. Abdominal diffusion-weighted MRIs of both groups were retrospectively reviewed. Diabetes-related clinical parameters were recorded. Results: The difference between the mean ADC values of the patient group and the control group was significant (p = 0.012). It was also found that the mean pancreatic ADC values of diabetic patients and the control group significantly differed (p = 0.02). Besides, there were positive correlations between the mean pancreatic ADC values and age, Hb1Ac level, treatment type, and disease duration (p < 0.05). While eGFR values positively correlated with the mean renal ADC values (p < 0.05), there were negative correlations between such values and age, serum creatinine level, and disease duration (p < 0.05). Conclusion: Renal and pancreatic ADC values of diabetic patients could potentially play a role, as markers of renal and pancreatic functions, in clinical decisions in the follow-up of such patients. © TÜBİTAK.
dc.identifier.doi10.3906/sag-2011-176
dc.identifier.endpage1295
dc.identifier.issn1300-0144
dc.identifier.issue3
dc.identifier.pmid33535733
dc.identifier.scopus2-s2.0-85109577354
dc.identifier.scopusqualityQ1
dc.identifier.startpage1289
dc.identifier.trdizinid482775
dc.identifier.urihttps://doi.org/10.3906/sag-2011-176
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/482775
dc.identifier.urihttps://hdl.handle.net/20.500.12587/23506
dc.identifier.volume51
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTurkiye Klinikleri
dc.relation.ispartofTurkish Journal of Medical Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241229
dc.subjectDiabetes mellitus; Diffusion-weighted imagin; Kidney; Magnetic resonance imaging; Pancreas
dc.titlePancreas and kidney changes in type 2 diabetes patients: The role of diffusion-weighteimaging
dc.typeArticle

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