Efficacy of clomipramine, sertraline and terazosin treatments in premature ejaculation

dc.contributor.authorTuncel, Altug
dc.contributor.authorAslan, Yilmaz
dc.contributor.authorBasar, M. Murad
dc.contributor.authorAtan, Ali
dc.date.accessioned2020-06-25T17:48:01Z
dc.date.available2020-06-25T17:48:01Z
dc.date.issued2008
dc.descriptionASLAN, YILMAZ/0000-0003-0670-6840
dc.description.abstractAim: To compare the efficacy of oral domipramine, sertraline and terazosin to placebo in premature ejaculation. Materials and Methods: A total of 90 patients aged from 20 to 58 years were enrolled in this study. Patients were randomized into 4 groups. Group 1 (n: 22) took placebo and served as controls. Group 2 (n: 23) patients took 25 mg clomipramine HCl nightly; Group 3 (n: 20). 50 mg sertraline nightly; and Group 4 (n: 25) 5 mg terazosin nightly. The medications were used for two months. After 8 sexual attempts, the patients' clinical responses were assessed using the patient self-description method. Clinical responses were classified as "no change", "improvement" and "under control". Success was described as improvement + under control. Results: Success rates were 36.3% in Group 1, 91.3% in Group 2, 90% in Group 3 and 76% in Group 4. Although the efficacy of each medical treatment was superior to placebo (P = 0.001), no significant difference in efficacy was found between the medical treatment groups (P = 0.537). Conclusions: Clomipramine, sertraline and terazosin are more efficient than placebo. No significant difference was observed in terms of efficacy among these three medical treatments.en_US
dc.identifier.citationTuncel, A., Aslan, Y., Başar, M. M., Atan, A. (2008). Efficacy of clomipramine, sertraline and terazosin treatments in premature ejaculation. Turkish Journal of Medical Sciences, 38(1), 59 - 64.en_US
dc.identifier.endpage64en_US
dc.identifier.issn1300-0144
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-40449102959
dc.identifier.scopusqualityQ1
dc.identifier.startpage59en_US
dc.identifier.trdizinid78838
dc.identifier.urihttps://hdl.handle.net/20.500.12587/4237
dc.identifier.volume38en_US
dc.identifier.wosWOS:000254179000010
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherTubitak Scientific & Technical Research Council Turkeyen_US
dc.relation.ispartofTurkish Journal Of Medical Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectpremature ejaculationen_US
dc.subjecttreatmenten_US
dc.subjectantidepressanten_US
dc.subjectalpha blockeren_US
dc.titleEfficacy of clomipramine, sertraline and terazosin treatments in premature ejaculationen_US
dc.typeArticle

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