Efficacy of clomipramine, sertraline and terazosin treatments in premature ejaculation
dc.contributor.author | Tuncel, Altug | |
dc.contributor.author | Aslan, Yilmaz | |
dc.contributor.author | Basar, M. Murad | |
dc.contributor.author | Atan, Ali | |
dc.date.accessioned | 2020-06-25T17:48:01Z | |
dc.date.available | 2020-06-25T17:48:01Z | |
dc.date.issued | 2008 | |
dc.description | ASLAN, YILMAZ/0000-0003-0670-6840 | |
dc.description.abstract | Aim: To compare the efficacy of oral domipramine, sertraline and terazosin to placebo in premature ejaculation. Materials and Methods: A total of 90 patients aged from 20 to 58 years were enrolled in this study. Patients were randomized into 4 groups. Group 1 (n: 22) took placebo and served as controls. Group 2 (n: 23) patients took 25 mg clomipramine HCl nightly; Group 3 (n: 20). 50 mg sertraline nightly; and Group 4 (n: 25) 5 mg terazosin nightly. The medications were used for two months. After 8 sexual attempts, the patients' clinical responses were assessed using the patient self-description method. Clinical responses were classified as "no change", "improvement" and "under control". Success was described as improvement + under control. Results: Success rates were 36.3% in Group 1, 91.3% in Group 2, 90% in Group 3 and 76% in Group 4. Although the efficacy of each medical treatment was superior to placebo (P = 0.001), no significant difference in efficacy was found between the medical treatment groups (P = 0.537). Conclusions: Clomipramine, sertraline and terazosin are more efficient than placebo. No significant difference was observed in terms of efficacy among these three medical treatments. | en_US |
dc.identifier.citation | Tuncel, A., Aslan, Y., Başar, M. M., Atan, A. (2008). Efficacy of clomipramine, sertraline and terazosin treatments in premature ejaculation. Turkish Journal of Medical Sciences, 38(1), 59 - 64. | en_US |
dc.identifier.endpage | 64 | en_US |
dc.identifier.issn | 1300-0144 | |
dc.identifier.issue | 1 | en_US |
dc.identifier.scopus | 2-s2.0-40449102959 | |
dc.identifier.scopusquality | Q1 | |
dc.identifier.startpage | 59 | en_US |
dc.identifier.trdizinid | 78838 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12587/4237 | |
dc.identifier.volume | 38 | en_US |
dc.identifier.wos | WOS:000254179000010 | |
dc.identifier.wosquality | N/A | |
dc.indekslendigikaynak | Web of Science | |
dc.indekslendigikaynak | Scopus | |
dc.indekslendigikaynak | TR-Dizin | |
dc.language.iso | en | |
dc.publisher | Tubitak Scientific & Technical Research Council Turkey | en_US |
dc.relation.ispartof | Turkish Journal Of Medical Sciences | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | premature ejaculation | en_US |
dc.subject | treatment | en_US |
dc.subject | antidepressant | en_US |
dc.subject | alpha blocker | en_US |
dc.title | Efficacy of clomipramine, sertraline and terazosin treatments in premature ejaculation | en_US |
dc.type | Article |
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