The effect of photobiomodulation on total amount of substance P in gingival crevicular fluid: placebo-controlled randomized clinical trial

Basit Öğe Kaydı
dc.contributor.authorYildiz, Ezgi Doganay
dc.contributor.authorArslan, Hakan
dc.contributor.authorKoseoglu, Serhat
dc.contributor.authorArabaci, Taner
dc.contributor.authorYildiz, Dursun Anil
dc.contributor.authorSavran, Levent
dc.date.accessioned2020-06-25T18:34:12Z
dc.date.available2020-06-25T18:34:12Z
dc.date.issued2019
dc.departmentKırıkkale Üniversitesi
dc.descriptionSavran, Levent/0000-0001-8824-3207
dc.description.abstractTo investigate the effect of photobiomodulation (PBM) and placebo on total amount of substance P in gingival crevicular fluid (GCF) pre- and postoperatively. Twenty-six patients having tooth with symptomatic apical periodontitis were enrolled in this study. GCF was collected preoperatively. The patients were assigned into two groups (n=13), as follows: placebo and PBM. Sampling was repeated 7days after root canal treatment. Two independent samples T test was used for analyzing of the differences between preoperative and postoperative substance P levels in GCF (p=.05). The Pearson correlation analysis was used for determination of correlation among substance P levels and other variables. For placebo group, there is no significant difference between preoperative and postoperative total amounts of substance P level (p=0.553). For PBM group, postoperative total amount of substance P level was significantly higher than those of preoperative level (p=0.005). Within the limitation of the present study, PBM has immunomodulation effect linked to the modulation of the total amount of substance P in the gingival crevicular fluid. Thai Clinical Trials Registry: TCTR20161228002en_US
dc.description.sponsorshipDepartment of Endodontics, Erzurum, Turkeyen_US
dc.description.sponsorshipThe work was supported by the Department of Endodontics, Erzurum, Turkey.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1007/s10103-018-2625-3
dc.identifier.endpage523en_US
dc.identifier.issn0268-8921
dc.identifier.issn1435-604X
dc.identifier.issue3en_US
dc.identifier.pmid30171442
dc.identifier.scopus2-s2.0-85052834572
dc.identifier.scopusqualityQ1
dc.identifier.startpage517en_US
dc.identifier.urihttps://doi.org/10.1007/s10103-018-2625-3
dc.identifier.urihttps://hdl.handle.net/20.500.12587/7821
dc.identifier.volume34en_US
dc.identifier.wosWOS:000461371500011
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer London Ltden_US
dc.relation.ispartofLasers In Medical Science
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSubstance Pen_US
dc.subjectPhotobiomodulationen_US
dc.subjectPostoperative painen_US
dc.subjectGingival crevicular fluiden_US
dc.titleThe effect of photobiomodulation on total amount of substance P in gingival crevicular fluid: placebo-controlled randomized clinical trialen_US
dc.typeArticle

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