Effects of GSM-like Radiofrequency on distortion product otoacoustic emissions of rabbits: Comparison of infants versus adults

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dc.contributor.authorBudak, Gürer G.
dc.contributor.authorMuluk, Nuray Bayar
dc.contributor.authorBudak, Bilgehan
dc.contributor.authorÖztürk, Göknur Güler
dc.contributor.authorApan, Alpaslan
dc.contributor.authorSeyhan, Nesrin
dc.date.accessioned2020-06-25T17:48:19Z
dc.date.available2020-06-25T17:48:19Z
dc.date.issued2009
dc.departmentKırıkkale Üniversitesi
dc.description.abstractobjectives: The aim of this study is to investigate the potential hazardous effects of 1800 MHz Global System for Mobile Communications-like (GSM-like) Radiofrequency (RF) exposure on the cochlear functions of female infant and adult rabbits by measuring Distortion Product Otoacoustic Emission (DPOAE) response amplitudes. Methods: Eighteen each one-month-old New Zealand White female rabbits and eighteen each 13-month-old adult rabbits were included into the study. They were randomly divided into four groups. Nine infant rabbits (Group 1) were not exposed to 1800 MHz GSM-like RF (Infant Control, C-In). Nine infant rabbits (Group 2) were exposed to 1800 MHz GSM-like RF, 15 min daily for 7 days after they reached one-month of age (Infant RF, RF-In). Nine adult rabbits were not exposed to 1800 MHz GSM-like RF, 15 min daily for 7 (Adult Control, C-Ad). Nine adult rabbits were exposed to 1800 MHz GSM-like RF, 15 min daily for 7 days (Adult RF, RF-Ad). Cochlear functions were assessed by DPOAEs at 1.0-8.0 kHz. Results: At 1.0-2.0 and 6.0 kHz, the mean DPOAE values of Group 2 were significantly higher than that of Group 1. At 3.0-8.0 kHz, the mean DPOAE values of Group 4 were significantly lower than that of Group 1. At 6.0-8.0 kHz, the mean DPOAE values of Group 2 were significantly higher than that of Group 3. At 1.0-8.0 kHz, the mean DPOAE values of Group 4 were significantly lower than that of Group 2. At 1.08.0 kHz, the mean DPOAE values of Group 4 were significantly lower than that of Group 3. Conclusion: Harmful effects of GSM-like 1800 MHz RF exposure was detected more in the adult female rabbits than infant female rabbits by DPOAE measurement. Prolonged exposure and hyperthermia related to the power density of applied RFR, increasing the temperature in the ear canal, may decrease the DPOAE amplitudes. Water containing medium in the middle ear of infant rabbits may play the protective role **from the RF damage. (C) 2009 Elsevier Ireland Ltd. All rights reserved.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1016/j.ijporl.2009.04.020
dc.identifier.endpage1147en_US
dc.identifier.issn0165-5876
dc.identifier.issn1872-8464
dc.identifier.issue8en_US
dc.identifier.pmid19477533
dc.identifier.scopus2-s2.0-67649114154
dc.identifier.scopusqualityQ2
dc.identifier.startpage1143en_US
dc.identifier.urihttps://doi.org/10.1016/j.ijporl.2009.04.020
dc.identifier.urihttps://hdl.handle.net/20.500.12587/4405
dc.identifier.volume73en_US
dc.identifier.wosWOS:000268219700016
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier Ireland Ltden_US
dc.relation.ispartofInternational Journal Of Pediatric Otorhinolaryngology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject1800 MHz GSM-like Radiofrequency (RF)en_US
dc.subjectCochleaen_US
dc.subjectDistortion product otoacoustic emissions (DPOAE)en_US
dc.subjectAdulten_US
dc.subjectInfanten_US
dc.subjectRabbitsen_US
dc.titleEffects of GSM-like Radiofrequency on distortion product otoacoustic emissions of rabbits: Comparison of infants versus adultsen_US
dc.typeArticle

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