Effect of Locally Applied bFGF on Implant Stability: Biomechanical Evaluation of 2 Different Implant Surfaces in Rabbits

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dc.contributor.authorKartal, Yasemin
dc.contributor.authorUcok, Cahit
dc.contributor.authorOzgul, Ozkan
dc.contributor.authorKocyigit, Ismail Doruk
dc.contributor.authorSuer, Berkay Tolga
dc.date.accessioned2020-06-25T18:12:10Z
dc.date.available2020-06-25T18:12:10Z
dc.date.issued2014
dc.departmentKırıkkale Üniversitesi
dc.description.abstractObjectives: The aim of this study was to evaluate the implant stability with the addition of local application of basic fibroblast growth factor (bFGF) during the osseointegration of 2 different dental implant surfaces using rabbit tibia model. Materials and Methods: Fifty-six dental implants, 28 of hydrophilic surface (SLActive) and 28 of hydrophobic surface (OsseoSpeed), were placed in 14 mature New Zealand rabbits. The rabbits each received both SLActive and OsseoSpeed implants per tibia, and bFGF was applied locally on 1 randomly selected tibia. Half of the subjects were killed at the fourth week of healing period, and the other half were killed at the twelfth week. Stabilization was assessed using resonance frequency analysis (RFA) and removal torque value (RTV). Results: The local application of bFGF was found to enhance osseointegration, especially at the fourth week of healing period after application (P = 0.046). RFAs and RTVs were found to be higher in bFGF-treated implant with hydrophilic surfaces when compared with both bFGF-treated hydrophobic implants and nontreated hydrophilic controls. Conclusion: Local application of bFGF seems to increase the stabilization values in implants with hydrophilic surfaces and those with hydrophobic surfaces.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1097/ID.0000000000000104
dc.identifier.endpage470en_US
dc.identifier.issn1056-6163
dc.identifier.issue4en_US
dc.identifier.pmid25051415
dc.identifier.scopus2-s2.0-84905035220
dc.identifier.scopusqualityN/A
dc.identifier.startpage463en_US
dc.identifier.urihttps://doi.org/10.1097/ID.0000000000000104
dc.identifier.urihttps://hdl.handle.net/20.500.12587/5771
dc.identifier.volume23en_US
dc.identifier.wosWOS:000340373100016
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofImplant Dentistry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectbFGFen_US
dc.subjectosseointegrationen_US
dc.subjectimplant surfaceen_US
dc.titleEffect of Locally Applied bFGF on Implant Stability: Biomechanical Evaluation of 2 Different Implant Surfaces in Rabbitsen_US
dc.typeArticle

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