The effect of varicocele on seminal plasma and serum inhibin-B levels in adolescent and adult men

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dc.contributor.authorBasar, M. Murad
dc.contributor.authorKisa, Ucler
dc.contributor.authorTuglu, Devrim
dc.contributor.authorKacmaz, Murat
dc.contributor.authorBasar, Halil
dc.date.accessioned2020-06-25T17:51:17Z
dc.date.available2020-06-25T17:51:17Z
dc.date.issued2010
dc.departmentKırıkkale Üniversitesi
dc.descriptionKISA, Ucler/0000-0002-8131-6810
dc.description.abstractIn the present study, the relationship between serum/seminal plasma and serum FSH and seminal parameters was evaluated in adults and adolescent varicocele patients and compared with normal fertile cases. A total of 50 adult patients with varicocele (Group-1) and 50 adolescents with varicocele (Group-2) were enrolled into the study. Fifty fertile cases without any scrotal pathology were accepted as control group (Group-3). Serum gonadotropin, sex steroids and serum and seminal plasma inhibin-B levels were measured, and semen analysis was performed after 2 and 5 days of sexual abstinence. All parameters were compared among three groups by using one-way ANOVA test. There were statistically significant differences among three groups on seminal parameters due to disturbed spermatogenesis in patients with varicocele (P < 0.05). However, there were not statistical differences between serum and seminal plasma Inhibin-B levels among groups. In varicocele patients, serum inhibin-B levels showed negative and significant correlation only with FSH levels (r = -0.253, P = 0.011). On the contrary, neither serum nor seminal plasma inhibin-B levels showed significant correlation with seminal parameters. While varicocele affects different mechanisms in the regulation of spermatogenesis in testes, serum and seminal plasma inhibin-B have not any role in decreased spermatogenesis in varicocele.en_US
dc.description.sponsorshipResearch Found of University of KirikkaleKirikkale University [03/08.03.17]en_US
dc.description.sponsorshipThis study was supported by Research Found of University of Kirikkale (03/08.03.17). This study was presented in the 28th Congress of SIU in Cape Town.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1007/s11255-009-9605-2
dc.identifier.endpage51en_US
dc.identifier.issn0301-1623
dc.identifier.issue1en_US
dc.identifier.pmid19590975
dc.identifier.scopus2-s2.0-77950917206
dc.identifier.scopusqualityQ2
dc.identifier.startpage47en_US
dc.identifier.urihttps://doi.org/10.1007/s11255-009-9605-2
dc.identifier.urihttps://hdl.handle.net/20.500.12587/4783
dc.identifier.volume42en_US
dc.identifier.wosWOS:000275991900008
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringeren_US
dc.relation.ispartofInternational Urology And Nephrology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectFSHen_US
dc.subjectInfertilityen_US
dc.subjectInhibin-Ben_US
dc.subjectSpermatogenesisen_US
dc.subjectVaricoceleen_US
dc.titleThe effect of varicocele on seminal plasma and serum inhibin-B levels in adolescent and adult menen_US
dc.typeArticle

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