Cardiac Troponin T in Children With Acute Rheumatic Carditis

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dc.contributor.authorOzdemir, Osman
dc.contributor.authorOguz, Deniz
dc.contributor.authorAtmaca, Emel
dc.contributor.authorSanli, Cihat
dc.contributor.authorYildirim, Ayse
dc.contributor.authorOlgunturk, Rana
dc.date.accessioned2020-06-25T17:52:20Z
dc.date.available2020-06-25T17:52:20Z
dc.date.issued2011
dc.departmentKırıkkale Üniversitesi
dc.description.abstractThe existence of cardiac damage in active rheumatic carditis patients is unknown, especially in those without pericarditis. The aim of this study was to determine cardiac myocyte damage using cardiac troponin T (cTnT) measurements in active rheumatic carditis. The levels of creatine kinase MB isoenzyme (CK-MB), cTnT, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), cardiothoracic ratio (CTR), and fractional shortening (FS) were compared using Mann-Whitney U test between 28 patients with active rheumatic carditis and 32 controls (healthy children). Association of cTnT levels with ESR, CRP, and CTR was evaluated with Spearman correlation analysis. ESR, CRP, cTnT levels, and CTR were statistically higher in the patients than in the controls. There were no differences between the groups for CK-MB levels and FS. No relationships were found between cTnT levels and ESR, CRP, and CTR in the patient group. The results of the study suggest that when cTnT levels are within non-pathological range, there is no serious cardiac damage; however, statistically significant increases in cTnT levels may indicate minor damages in patients with active carditis due to acute rheumatic fever.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1007/s00246-010-9814-6
dc.identifier.endpage58en_US
dc.identifier.issn0172-0643
dc.identifier.issn1432-1971
dc.identifier.issue1en_US
dc.identifier.pmid20957477
dc.identifier.scopus2-s2.0-78751629099
dc.identifier.scopusqualityQ2
dc.identifier.startpage55en_US
dc.identifier.urihttps://doi.org/10.1007/s00246-010-9814-6
dc.identifier.urihttps://hdl.handle.net/20.500.12587/5133
dc.identifier.volume32en_US
dc.identifier.wosWOS:000286065400008
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringeren_US
dc.relation.ispartofPediatric Cardiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAcute rheumatic feveren_US
dc.subjectCarditisen_US
dc.subjectTroponin Ten_US
dc.titleCardiac Troponin T in Children With Acute Rheumatic Carditisen_US
dc.typeArticle

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