The effect of smoking on gingival crevicular fluid peptidoglycan recognition protein-1 level following initial periodontal therapy in chronic periodontitis

dc.contributor.authorKarsiyaka Hendek, Meltem
dc.contributor.authorKısa, Üçler
dc.contributor.authorOlgun, Ebru
dc.date.accessioned2020-06-25T18:35:10Z
dc.date.available2020-06-25T18:35:10Z
dc.date.issued2020
dc.departmentKırıkkale Üniversitesi
dc.descriptionKISA, Ucler/0000-0002-8131-6810
dc.description.abstractObjective To determine the effect of smoking on peptidoglycan recognition protein (PGRP)-1 levels in gingival crevicular fluid (GCF) in smokers and non-smokers with chronic periodontitis (CP) following initial periodontal therapy. Subjects and Methods A total of 40 patients with CP (20 smokers (S + CP) and 20 non-smokers (S-CP)) and 40 subjects with healthy periodontium (20 smokers (S + PH) and 20 non-smokers (S-PH)), comprising 80 subjects, were included in this study. Baseline GCF samples were obtained from all subjects, and clinical periodontal measurements were recorded. In patients who had received initial periodontal therapy, GCF samples were obtained and all clinical periodontal measurements were recorded again during the 6th-8th weeks. GCF PGRP-1 levels were analyzed by enzyme-linked immunosorbent assay. Results At baseline, GCF PGRP-1 levels were significantly higher in both groups with CP than in both groups with healthy periodontium, whereas these levels were significantly lower in S + CP than in S-CP. GCF PGRP-1 levels decreased significantly in both CP groups after periodontal therapy, and this reduction was significantly greater in non-smokers than in smokers. Conclusion Smoking might have a suppressive effect on GCF PGRP-1 levels in CP. Initial periodontal therapy is effective in decreasing GCF PGRP-1 levels in both smokers and non-smokers with CP.en_US
dc.description.sponsorshipScientific Research Project Fund of Kirikkale UniversityKirikkale University [2016/026]en_US
dc.description.sponsorshipThe Scientific Research Project Fund of Kirikkale University, Grant/Award Number: The project number: 2016/026en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1111/odi.13207
dc.identifier.endpage172en_US
dc.identifier.issn1354-523X
dc.identifier.issn1601-0825
dc.identifier.issue1en_US
dc.identifier.pmid31587460
dc.identifier.scopus2-s2.0-85074375417
dc.identifier.scopusqualityQ1
dc.identifier.startpage166en_US
dc.identifier.urihttps://doi.org/10.1111/odi.13207
dc.identifier.urihttps://hdl.handle.net/20.500.12587/8139
dc.identifier.volume26en_US
dc.identifier.wosWOS:000491204200001
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWileyen_US
dc.relation.ispartofOral Diseases
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectchronic periodontitisen_US
dc.subjectdental scalingen_US
dc.subjectgingival crevicular fluiden_US
dc.subjectPGLYRP1 proteinen_US
dc.subjectroot planingen_US
dc.subjectsmokingen_US
dc.titleThe effect of smoking on gingival crevicular fluid peptidoglycan recognition protein-1 level following initial periodontal therapy in chronic periodontitisen_US
dc.typeArticle

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