Central corneal thickness in patients with mild to moderate rosacea

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dc.contributor.authorOnaran, Zater
dc.contributor.authorKarabulut, Ayse Anil
dc.contributor.authorUsta, Gulsah
dc.contributor.authorOrnek, Kemal
dc.date.accessioned2020-06-25T17:52:26Z
dc.date.available2020-06-25T17:52:26Z
dc.date.issued2012
dc.departmentKırıkkale Üniversitesi
dc.descriptionusta, gulsah/0000-0002-0065-4384;
dc.description.abstractObjective: We aimed to evaluate central corneal thickness (CCT) in patients with rosacea in comparison to a healthy control group and to investigate any correlations by using the Schirmer test, tear break-up time (TBUT), and disease severity. Design: Prospective nonrandomized study. Participants: Patients with mild to moderate rosacea (n = 51) and a group of healthy individuals (n = 51) were included. Method: Patients were evaluated by a dermatologist; disease severity was determined and total rosacea severity score was calculated for each patient. CCT measurements were performed using ultrasonic pachymetry. Tear function tests, including Schirmer and TBUT, were also performed. Results: The mean CCT value was significantly lower in patients with rosacea than in the control group (544.91 +/- 29.41 mu m vs 559.40 +/- 24.18 mu m, p = 0.003). The mean Schirmer test value was significantly lower in patients than in controls (10.54 +/- 6.09 mm vs 19.13 +/- 4.24 mm, p < 0.0001), and the mean TBUT was shorter in the group with rosacea than in the controls (8.32 +/- 3.50 s vs 16.67 +/- 5.76 s, p < 0.0001). CCT values were found to be correlated with the Schirmer test values in the rosacea group (r = 0.33, p = 0.01). Conclusions: Patients with rosacea have thinner corneas, which could be attributed to the observed deteriorated tear function parameters. Candidates for corneal photoablation surgery should be evaluated regarding rosacea disease because the postoperative period could be complicated by decreased ocular wetting and corneal thinning, even in overlooked mild forms.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1016/j.jcjo.2012.07.009
dc.identifier.endpage508en_US
dc.identifier.issn0008-4182
dc.identifier.issn1715-3360
dc.identifier.issue6en_US
dc.identifier.pmid23217504
dc.identifier.scopus2-s2.0-84875457967
dc.identifier.scopusqualityQ2
dc.identifier.startpage504en_US
dc.identifier.urihttps://doi.org/10.1016/j.jcjo.2012.07.009
dc.identifier.urihttps://hdl.handle.net/20.500.12587/5157
dc.identifier.volume47en_US
dc.identifier.wosWOS:000208859800028
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherCanadian Ophthal Socen_US
dc.relation.ispartofCanadian Journal Of Ophthalmology-Journal Canadien D Ophtalmologie
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleCentral corneal thickness in patients with mild to moderate rosaceaen_US
dc.typeArticle

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