Evaluation of liver damage after application of TVE in the rat model

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dc.contributor.authorDarılmaz, Gökhan
dc.contributor.authorTopaloğlu, Serdar
dc.contributor.authorTopaloglu, E
dc.contributor.authorÖzel, Helin
dc.contributor.authorSaygun, Oral
dc.contributor.authorAvşar, Fatih Mehmet
dc.contributor.authorHengirmen, Süleyman
dc.date.accessioned2020-06-25T17:40:18Z
dc.date.available2020-06-25T17:40:18Z
dc.date.issued2005
dc.departmentKırıkkale Üniversitesi
dc.description.abstractIntroduction. The aim of this study was to investigate the effects of total vascular exclusion (TVE) on the liver during the early period of reperfusion. Materials and methods. Forty Wistar-Albino rats were divided into four groups. Portal pedicle clamping (groups 1 and 2) or TVE (groups 3 and 4) were applied for 10 minutes. Samples were collected at the time of clamp release (groups 1 and 3) and at 30 minutes of reperfusion (groups 2 and 4). We examined oxidative injury to and histopathology of the liver. Results. Oxidative stress was more prominent with TVE application. Significant alterations were shown in hepatic superoxide dismutase, catalase, glutathione, and glutathione S-transferase levels. The levels of malondialdehyde and myeloperoxidase were not altered significantly. Conclusion. Inflow-outflow occlusion of the liver causes more oxidative stress compared with inflow occlusion.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1016/j.transproceed.2005.11.002
dc.identifier.endpage4552en_US
dc.identifier.issn0041-1345
dc.identifier.issn1873-2623
dc.identifier.issue10en_US
dc.identifier.pmid16387167
dc.identifier.scopus2-s2.0-29544432486
dc.identifier.scopusqualityQ3
dc.identifier.startpage4550en_US
dc.identifier.urihttps://doi.org/10.1016/j.transproceed.2005.11.002
dc.identifier.urihttps://hdl.handle.net/20.500.12587/3384
dc.identifier.volume37en_US
dc.identifier.wosWOS:000234412900103
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier Science Incen_US
dc.relation.ispartofTransplantation Proceedings
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleEvaluation of liver damage after application of TVE in the rat modelen_US
dc.typeArticle

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