MIB-1 expression in odontogenic epithelial rests, epithelium of healthy oral mucosa and epithelium of selected odontogenic cysts - An immunohistochemical study

Simple item page
dc.contributor.authorSaraçoğlu, U.
dc.contributor.authorKurt, B.
dc.contributor.authorGünhan, O.
dc.contributor.authorGüven, O.
dc.date.accessioned2020-06-25T17:40:35Z
dc.date.available2020-06-25T17:40:35Z
dc.date.issued2005
dc.departmentKırıkkale Üniversitesi
dc.description.abstractThe aim of this study is to investigate the proliferative potential of rests of odontogenic epithelium found in follicles of unerupted teeth, epithelium of oral mucosa and epithelial linings of various odontogenic cysts. MIB-1 expression was studied in the rests of odontogenic epithelium (n = 10), healthy oral mucosa (17 = 10), odontogenic keratocysts (n = 10) and other odontogenic cysts (n = 10) using an avidin-biotin peroxidase technique on paraffin sections. The number of positively stained cells was counted on 10 representative areas of epithelium using a x 40 objective. The average number of MIB-1 positive cells in each group was calculated. No MIB-1 positive cells were seen in the rests of odontogenic epithelium. The mean numbers of MIB-1 positive cells detected within the epithelium of oral mucosa, and of radicular and dentigerous cysts were similar. The number of MIB-1 positive cells was found to be increased in the presence of marked inflammatory cell infiltration. The highest number of MIB-1 positive cells was seen in the keratocysts. These findings suggest that removal of an unerupted tooth to prevent the possibility of neoplastic transformation of rests of odontogenic epithelium is not a justifiable rationale.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1016/j.ijom.2004.09.005
dc.identifier.endpage435en_US
dc.identifier.issn0901-5027
dc.identifier.issn1399-0020
dc.identifier.issue4en_US
dc.identifier.pmid16053855
dc.identifier.scopus2-s2.0-18244402873
dc.identifier.scopusqualityQ1
dc.identifier.startpage432en_US
dc.identifier.urihttps://doi.org/10.1016/j.ijom.2004.09.005
dc.identifier.urihttps://hdl.handle.net/20.500.12587/3497
dc.identifier.volume34en_US
dc.identifier.wosWOS:000229449100017
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherChurchill Livingstoneen_US
dc.relation.ispartofInternational Journal Of Oral And Maxillofacial Surgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMIB-1en_US
dc.subjectodontogenic epithelial resten_US
dc.subjectodontogenic cysten_US
dc.subjectimmunohistochemistryen_US
dc.titleMIB-1 expression in odontogenic epithelial rests, epithelium of healthy oral mucosa and epithelium of selected odontogenic cysts - An immunohistochemical studyen_US
dc.typeArticle

Files

Original bundle
Now showing 1 - 1 of 1
[ X ]
Name:
MIB-1 expression in odontogenic epithelial rests, epithelium of healthy oral mucosa and epithelium of selected odontogenic cysts - An immunohistochemical study.pdf
Size:
244.5 KB
Format:
Adobe Portable Document Format
Description:
Tam Metin/Full Text
Download

Collections

WOS İndeksli Yayınlar Koleksiyonu
Makale Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu