Postoperative magnesium sulphate infusion reduces analgesic requirements in spinal anaesthesia

Basit Öğe Kaydı
dc.contributor.authorApan, A
dc.contributor.authorBuyukkocak, U
dc.contributor.authorOzcan, S
dc.contributor.authorSari, E
dc.contributor.authorBasar, H
dc.date.accessioned2020-06-25T17:40:03Z
dc.date.available2020-06-25T17:40:03Z
dc.date.issued2004
dc.departmentKırıkkale Üniversitesi
dc.description.abstractBackground and objectives: Magnesium sulphate infusion during general anaesthesia reduces anaesthetic consumption and analgesic requirements. The aim of this study was to assess the effects of postoperative magnesium infusion on duration of block, sedation and analgesic consumption after spinal anaesthesia. Methods: Fifty ASA I-II patients were included in the randomized double blind study. Spinal anaesthesia was performed at L3-4 or L4-5 interspace with 12.5 mg 0.5% heavy bupivacaine, using a 25G Quincke needle. Patients received a 5 mg kg(-1) bolus of magnesium sulphate followed by a 500 mg h(-1) infusion or saline in the same volumes for 24 h. Time to first pain, analgesic request, return of motor function, visual analogue pain and sedation scores were evaluated every 4 h during the 24 h postoperative period. The t- and U-tests were used for statistical analyses. Data were expressed as mean +/- SD, with P < 0.05 being considered significant. Results: Vital signs were stable during spinal anaesthesia and postoperative period. When compared to the control group, time to analgesic need was increased and total analgesic consumption was reduced in the magnesium group (meperidine consumption 60.0 +/- 73.1 mg control group, 31.8 +/- 30.7 mg magnesium group, P = 0.02). Conclusions: Magnesium sulphate infusion may be used as an adjunct for reducing analgesic consumption after spinal anaesthesia.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1017/S026502150400002X
dc.identifier.endpage769en_US
dc.identifier.issn0265-0215
dc.identifier.issue10en_US
dc.identifier.pmid15678729
dc.identifier.scopus2-s2.0-14244267605
dc.identifier.scopusqualityQ1
dc.identifier.startpage766en_US
dc.identifier.urihttps://doi.org/10.1017/S026502150400002X
dc.identifier.urihttps://hdl.handle.net/20.500.12587/3230
dc.identifier.volume21en_US
dc.identifier.wosWOS:000226195500002
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherGreenwich Medical Media Ltden_US
dc.relation.ispartofEuropean Journal Of Anaesthesiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectanaesthesiaen_US
dc.subjectspinalen_US
dc.subjectbupivacaineen_US
dc.subjectmagnesium sulphateen_US
dc.subjectinfusionen_US
dc.subjectanalgesiaen_US
dc.subjectpostoperativeen_US
dc.subjectpotentiationen_US
dc.subjectmeperidineen_US
dc.titlePostoperative magnesium sulphate infusion reduces analgesic requirements in spinal anaesthesiaen_US
dc.typeArticle

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