Meningoencephalitis caused by pathogenic Sarcocystis species in a naturally infected sheep in Turkey

dc.contributor.authorAlasonyalilar-Demirer, Aylin
dc.contributor.authorKahraman, M. Mufit
dc.contributor.authorAkkoc, Ahmet
dc.contributor.authorErturkuner, S. Pelin
dc.contributor.authorGuzel, E. Elif
dc.contributor.authorKul, Oguz
dc.contributor.authorIpek, Volkan
dc.date.accessioned2020-06-25T18:23:44Z
dc.date.available2020-06-25T18:23:44Z
dc.date.issued2017
dc.departmentKırıkkale Üniversitesi
dc.descriptionMeydanli, E. Elif Guzel/0000-0001-9072-3322; IPEK, VOLKAN/0000-0001-5874-7797
dc.description.abstractA 3-year-old sheep was examined after an acute onset of hind limb paralysis and ataxia. At necropsy, central nervous system, pulmonary and intestinal hyperaemia and ecchymoses in the aortic arch were observed. Main microscopic lesions were confined to the heart, cerebrum and cerebellum. There were a multifocal mild myocarditis and non-suppurative meningoencephalitis together with protozoal cysts in the heart and the brain. Protozoal cystic structures were observed within many of the myocardial fibers as well as in the cerebrum and cerebellum. Using light microscopy it could not be morphologically determined whether these organisms were Toxoplasma (T.) gondii or Neospora (N.) caninum. Additional diagnostic methods like immunohistochemistry and polymerase chain reaction provided differentiation of Sarcocystis from T. gondii and N. caninum. Transmission electron microscopy demonstrated characteristic features of Sarcocystis sp. as previously described. This is the first confirmed diagnosis of Sarcocystis sp. in the central nervous system of a sheep from Turkey.en_US
dc.description.sponsorshipUludag University Research Foundation, Bursa, Turkey [OUAP [V] 2013/28]en_US
dc.description.sponsorshipThis study was supported by a grant from the Uludag University Research Foundation, Bursa, Turkey (project number OUAP [V] 2013/28). The authors would like to thank Nicole Cohart for English editing support and Deniz Seyrek-Intas for German editing support.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.15653/TPG-141038
dc.identifier.endpage46en_US
dc.identifier.issn1434-1220
dc.identifier.issn2567-5834
dc.identifier.issue1en_US
dc.identifier.pmid28116411
dc.identifier.scopus2-s2.0-85014031294
dc.identifier.scopusqualityQ4
dc.identifier.startpage42en_US
dc.identifier.urihttps://doi.org/10.15653/TPG-141038
dc.identifier.urihttps://hdl.handle.net/20.500.12587/7176
dc.identifier.volume45en_US
dc.identifier.wosWOS:000394411200005
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherGeorg Thieme Verlag Kgen_US
dc.relation.ispartofTieraerztliche Praxis Ausgabe Grosstiere Nutztiere
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEncephalitisen_US
dc.subjectprotozoaen_US
dc.subjecthistopathologyen_US
dc.subjectelectron-microscopyen_US
dc.subjectdifferentiationen_US
dc.titleMeningoencephalitis caused by pathogenic Sarcocystis species in a naturally infected sheep in Turkeyen_US
dc.typeArticle

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