Magnesium sulphate infusion is not effective on discomfort or emergence phenomenon in paediatric adenoidectomy/tonsillectomy

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dc.contributor.authorApan, Alparslan
dc.contributor.authorAykaç, Esra
dc.contributor.authorKazkayasi, Mustafa
dc.contributor.authorDoğancı, Nur
dc.contributor.authorTahran, Filiz Datlı
dc.date.accessioned2020-06-25T17:49:04Z
dc.date.available2020-06-25T17:49:04Z
dc.date.issued2010
dc.departmentKırıkkale Üniversitesi
dc.description.abstractObjective: This study was performed to evaluate the possible influence of magnesium sulphate which has sedative and analgesic properties on sevoflurane-induced emergence agitation in paediatric patients undergoing adenoidectomy with or without tonsillectomy. Methods: One hundred and ten paediatric patients aged between 3 and 16 years were randomly allocated to the study. Propofol 2-2.5 mg kg(-1), vecuronium 0.1 mg kg(-1) and fentanyl 1 mu g kg(-1) were used for induction of anesthesia and sevoflurane at 1 MAC with nitrous oxide in oxygen (35%) mixture was administered as maintenance. Magnesium sulfate 30 mg kg(-1) in saline (20 mL) in the Group M, or equal volume of saline for controls (Group C) was started 10 min before and infused until the end of the operation. Recovery characteristics included time to extubation, eyes open, emergence and interaction. Patients were evaluated using Modified Aldrete Score (MAS), Pain/Discomfort Scale and Agitation Score. Side effects were determined during emergence and in the recovery. Results: Time to open eyes was significantly higher in the magnesium treatment group (Group C: 7.7 +/- 3.5, Group M: 12.7 +/- 17.5 min, p = 0.001). Agitation score was significantly lower in Group M at the 60th min (Group C: 1.3 +/- 0.7, Group M: 1.0 +/- 0.3, p = 0.005). Agitation or pain/discomfort scores in the resting observation periods were the same. The initial MAS value was lower in Group M (Group C: 5.0 +/- 1.9, Group M: 4.0 +/- 1.7, p = 0.003). There was no significant difference between groups regarding side effects. Conclusion: Magnesium sulphate infusion has no influence on sevoflurane-induced discomfort or emergence agitation. (C) 2010 Elsevier Ireland Ltd. All rights reserved.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1016/j.ijporl.2010.09.004
dc.identifier.endpage1371en_US
dc.identifier.issn0165-5876
dc.identifier.issn1872-8464
dc.identifier.issue12en_US
dc.identifier.pmid20880596
dc.identifier.scopus2-s2.0-78449268300
dc.identifier.scopusqualityQ2
dc.identifier.startpage1367en_US
dc.identifier.urihttps://doi.org/10.1016/j.ijporl.2010.09.004
dc.identifier.urihttps://hdl.handle.net/20.500.12587/4627
dc.identifier.volume74en_US
dc.identifier.wosWOS:000285176800005
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier Ireland Ltden_US
dc.relation.ispartofInternational Journal Of Pediatric Otorhinolaryngology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSevofluraneen_US
dc.subjectEmergenceen_US
dc.subjectAgitationen_US
dc.subjectMagnesium sulphateen_US
dc.subjectInfusionen_US
dc.titleMagnesium sulphate infusion is not effective on discomfort or emergence phenomenon in paediatric adenoidectomy/tonsillectomyen_US
dc.typeArticle

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