The expression of CD14 antigen in experimental encephalitic listeriosis in rabbits
Yükleniyor...
Tarih
2004
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Ecole Nationale Veterinaire Toulouse
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The present study examined the distribution of Listeria monocytogenes 1/2a (L.m. 1/2a) and the antigen CD14 by using immunohistochemical methods in the brain of healthy and experimentally infected rabbits with L.m. 1/2a. The ten New Zealand White rabbits were inoculated by intracerebral route, and 4 rabbits were used for control. Only the brains of the animals were removed during necropsy, and they were analysed by conventional histological techniques. By Haematoxylin and Eosin staining all L.m. 1/2a inoculated rabbits presented meningitis or meningoencephalitis. In healthy rabbits, the immunohistochemical staining of brains for CD14 was very slight and seen only in the lumen of the vessels, whereas, in infected rabbits the CD14 immunoreactivity was more prominent especially in inflammation areas of parenchyma and meninges. Moreover, the CD14 positive immunostainings were seen massively in L.m. positive inflamed areas. The present study provides the immunohistochemical expression of CD14 and L.monocytogenes antigen in the brain and a positive correlation was obtained between CD14 and this infectious agent.
Açıklama
/0000-0002-0636-4214
Anahtar Kelimeler
brain, CD14, immunohistochemistry, Listeria monocytogenes
Kaynak
Revue De Medecine Veterinaire
WoS Q Değeri
Q4
Scopus Q Değeri
N/A
Cilt
155
Sayı
3
Künye
closedAccess
