The expression of CD14 antigen in experimental encephalitic listeriosis in rabbits

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dc.contributor.authorKabakci, N
dc.contributor.authorYarim, M
dc.date.accessioned2020-06-25T17:40:10Z
dc.date.available2020-06-25T17:40:10Z
dc.date.issued2004
dc.departmentKırıkkale Üniversitesi
dc.description/0000-0002-0636-4214
dc.description.abstractThe present study examined the distribution of Listeria monocytogenes 1/2a (L.m. 1/2a) and the antigen CD14 by using immunohistochemical methods in the brain of healthy and experimentally infected rabbits with L.m. 1/2a. The ten New Zealand White rabbits were inoculated by intracerebral route, and 4 rabbits were used for control. Only the brains of the animals were removed during necropsy, and they were analysed by conventional histological techniques. By Haematoxylin and Eosin staining all L.m. 1/2a inoculated rabbits presented meningitis or meningoencephalitis. In healthy rabbits, the immunohistochemical staining of brains for CD14 was very slight and seen only in the lumen of the vessels, whereas, in infected rabbits the CD14 immunoreactivity was more prominent especially in inflammation areas of parenchyma and meninges. Moreover, the CD14 positive immunostainings were seen massively in L.m. positive inflamed areas. The present study provides the immunohistochemical expression of CD14 and L.monocytogenes antigen in the brain and a positive correlation was obtained between CD14 and this infectious agent.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.endpage155en_US
dc.identifier.issn0035-1555
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-2342587308
dc.identifier.scopusqualityN/A
dc.identifier.startpage151en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12587/3324
dc.identifier.volume155en_US
dc.identifier.wosWOS:000221704400004
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherEcole Nationale Veterinaire Toulouseen_US
dc.relation.ispartofRevue De Medecine Veterinaire
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectbrainen_US
dc.subjectCD14en_US
dc.subjectimmunohistochemistryen_US
dc.subjectListeria monocytogenesen_US
dc.titleThe expression of CD14 antigen in experimental encephalitic listeriosis in rabbitsen_US
dc.typeArticle

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